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For patients with vasodilatory shock that does not respond to high-dose vasopressors

ATS: Angiotensin II Improves BP in Vasodilatory Shock

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Angiotensin II effective for vasodilatory shock in patients not responding to conventional vasopressors
For participants in the Diabetes Prevention Program Outcomes Study

No Link to Cognition in Diabetes Prevention Program Study

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Intensive lifestyle intervention, metformin not tied to cognition
Patients with life-limiting illness often receive medications of questionable benefit given their remaining life span

Patients Often Prescribed Futile Drugs in Last Months of Life

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Researchers find many still prescribed long-term disease-preventing medications
Imatinib (Gleevec) may effectively treat severe refractory asthma

KIT Inhibition by Imatinib Helps Severe Refractory Asthma

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Improvement in airway hyperresponsiveness seen with imatinib versus placebo
Lower- and higher-dose elagolix are beneficial for women with endometriosis

Lower-, Higher-Dose Elagolix Beneficial for Endometriosis

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Higher percentage of women have clinical response for dysmenorrhea, non-menstrual pelvic pain
There is substantial variation in prescribing patterns of opioid medications for minor injuries across U.S. emergency rooms

Substantial Variation in Opioid Rx for Minor Injuries Across U.S.

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Laws limiting new opioid prescriptions to no more than a five-day supply could be beneficial
The first prescription of an antibiotic that the average U.S. adult with pneumonia receives is now ineffective in about a quarter of cases

ATS: First Abx Rx Doesn’t Work for ~25% of Pneumonia Cases

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One in four adult patients do not respond to initial prescription of antibiotic treatment
The injected drug Actemra (tocilizumab) has been approved by the U.S. Food and Drug Administration to treat adults with giant cell arteritis.

FDA Approves Actemra to Treat Giant Cell Arteritis

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New indication provides the first FDA-approved therapy specific to this type of vasculitis
Acute dietary nitrate supplementation using beetroot juice can decrease central sympathetic outflow at rest and during exercise

Beetroot Juice Can Reduce Central Sympathetic Outflow

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Dietary nitrate supplementation with beetroot juice tied to lower sympathetic outflow at rest, with exercise
Similar outcomes are seen for use of bivalirudin and heparin as anticoagulant agents in patients with ST-segment elevation myocardial infarction treated with radial primary percutaneous coronary intervention

Similar Outcomes for Bivalirudin, Heparin in STEMI With PCI

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No significant difference in rate of composite end point of death, myocardial infarction, or stroke