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Immediate antiretroviral initiation at HIV diagnosis is associated with greater bone mineral density declines compared with deferred initiation

In HIV, Greater BMD Decline for Immediate Versus Delayed ART

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After one year, change in bone mineral density was similar in the immediate and deferred groups
For well-trained cyclists

EPO Doping Has Little Effect on Real-World Cycling Performance

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Appears to improve high-intensity performance, not endurance or road race performance
Dutasteride for the treatment of benign prostatic hyperplasia may induce imbalance in metabolic function

Dutasteride Associated With Metabolic Safety Concerns

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Use of medication in BPH linked to higher hemoglobin A1c and LDL cholesterol levels
Many women at high risk for breast cancer do not take tamoxifen to prevent the disease

Many Women Have Questions, Concerns About Tamoxifen

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Study shows that normal symptoms of menopause are often attributed to tamoxifen
Depression

Psychological Risks Higher in Atopic Dermatitis Patients

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However, this does not translate into increased use of health care services, suicide
For select patients with advanced melanoma

Nivolumab Rx Beyond Progression Beneficial in Melanoma

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28 percent of patients treated beyond progression had lesion reduction >30 percent
Patients with remaining endogenous β-cell function after a decade of living with type 1 diabetes tend to have much higher levels of interleukin-35 than other patients with long-standing type 1 diabetes

T1DM Patients With Active β-Cell Function Differ Immunologically

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Findings for patients with remaining endogenous β-cell function after 10 or more years of T1DM
Many older Americans who have difficulty paying for their medications don't seek help in finding more economical options

Poll Finds Seniors Struggling With Drug Costs Don’t Seek Help

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Roughly half of older Americans don't, but those who do receive assistance from their doctor
There is insufficient evidence to support delaying several cutaneous surgical procedures in the setting of systemic isotretinoin therapy

Most Cutaneous Procedures Seem Safe During Isotretinoin Rx

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Mechanical dermabrasion and fully ablative laser not recommended in setting of systemic treatment
Metformin has therapeutic potential as a post-ischemic conditioning agent

Metformin Therapeutic As Post-Ischemic Conditioning Agent

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Metformin maintains cell viability and membrane stability of cardiomyoblast cells from ischemic injury