Chronic Dosing of Apricot Kernel Extract May Lead to Hypoxia
Self-prescription of kernel extract reported for five years; cyanide toxicity confirmed in blood analysis
Most Opioid Use Concentrated in Top 10 Percent of Users
Top 10 percent of users accounted for 76 percent of the total annual morphine equivalents
2017 Standards of Medical Care in Diabetes Released
Recommendations for T1D focus on monitoring, pharmacologic approaches to glycemic management
In HIV, Tissue Factor-Expressing Monocytes Trigger Coagulation
The anticoagulant Ixolaris blocked functional activity of tissue factor in vitro and in vivo
Risk of Prematurity, SGA Up for Women on Antiepileptic Drugs
Increased risk for women on AEDs for epilepsy or other indications; risk varies with drug used
Diverse Neurological Effects Linked to Anti-PD-1 Therapy
Complications seen after median of 5.5 cycles of anti-PD-1-inhibitors; include myopathy, neuropathies
Lidocaine Nerve Block Reduces Pain During IUD Insertion
Pain score lower among patients who receive lidocaine than those who receive placebo
Longer Progression-Free Survival for Durvalumab in NSCLC
Longer median progression-free survival from randomization, higher response rate with durvalumab
Median Cost of Cancer Drug Development $648.0 Million
Total revenue from sales of 10 drugs was $67.0 billion, with total R&D spending of $7.2 billion
ASBMR: Romosozumab Reduces Fracture Rate in Osteoporosis
Reduced risk of new vertebral fractures, nonvertebral fractures for romosozumab and alendronate
