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Polygenic risk can mimic major monogenic mutation in severe hypertriglyceridemia

Case Highlights Polygenic Risk in Severe Hypertriglyceridemia

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Patient with hypertriglyceridemia had polymorphisms producing triglyceride risk score of 19
While opioid abuse has decreased among younger Americans

SAMHSA: Opioid Abuse Up Among Older Adults

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Rates have doubled in people over 50, report says
For patients with type 2 diabetes mellitus

Fasting Plasma Glucose, HbA1c Linked to Alzheimer’s in T2DM

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Independent associations for FPG coefficient of variation and HbA1c CV in patients with T2DM
For patients with an adverse reaction to a statin

Continuing Statin After Adverse Rx Tied to Lower Cardiac Risk

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Continued statin prescription linked to lower incidence of cardiovascular events and death
Teens and adults with attention-deficit/hyperactivity disorder (ADHD) may have a lower risk of developing an alcohol or drug problem if they take medications to treat their ADHD

ADHD Rx Associated With a Lower Risk for Alcohol, Drug Abuse

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Linked to a 35 percent lower risk among men and 31 percent lower risk among women
Most primary care physicians can't identify all 11 risk factors for prediabetes

Survey Reveals Prediabetes Knowledge Gaps in Primary Care

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Fewer than one in 10 PCPs surveyed named all risk factors identified by American Diabetes Association
The rate of unfavorable features is increased in association with increasing MYCN copy number in patients with neuroblastoma

MYCN Copy Number Tied to Poor Features in Neuroblastoma

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Patients with MYCN gain had inferior outcomes, including lowest response rate after chemo
Provider- and site-level factors

Provider-, Site-Level Factors Linked to Testosterone Receipt

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Increased odds of prescribing testosterone for less experienced providers, endocrinologists, urologists
High-dose influenza vaccination can reduce risk of respiratory-related hospitalization among nursing home residents aged 65 years and older

High-Dose Flu Vaccine Cuts Admissions From Nursing Homes

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Rates of hospital admission lower compared with standard-dose vaccine in residents aged 65+
Injectable

Long-Acting Antiretroviral Injection Safe, Effective for HIV

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Cabotegravir + rilpivirine injection every four or eight weeks as effective as daily three-drug oral therapy