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Review: Levetiracetam Best Monotherapy for Partial Seizures

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First-line tx sodium valproate tops carbamazepine, topiramate for generalized onset seizures

FDA Approves Idhifa for Some With Acute Myeloid Leukemia

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For adults with relapsed or refractory AML who have an IDH2 genetic mutation

Less Than Half of Stroke Discharges Prescribed a Statin

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Prescribing differences by age, sex seen in 'Stroke Belt' in the southern U.S. versus rest of nation

Are Clinicians Overprescribing Gabapentinoids for Pain?

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Non-trivial side effects, no robust evidence for off-label use of gabapentinoids for other types of pain

FDA Approves Imbruvica to Treat Chronic Graft Versus Host Disease

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Drug sanctioned for patients with cGVHD who do not respond to other forms of therapy
Only about 61 percent of women with newly diagnosed gestational diabetes mellitus perform ≥80 percent of required self-monitoring of blood glucose tests

Poor Adherence to Self-Monitoring of Glucose in GDM

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Poor adherence tied to preeclampsia; poor post-prandial test timing tied to higher HbA1c at delivery
Isoniazid monotherapy

Meta-Analysis Compares Efficacy of Therapies for Preventing TB

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Isoniazid, rifampicin monotherapy, combination therapies can prevent active TB in latent TB infection
A comprehensive initiative

Comprehensive Initiative Has Positive Impact on Opioid Rx

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Reductions in all tracked outcomes, including 95% drop in brand name opioid-acetaminophen products
Some research has raised concerns about the safety of aspirin for heart failure patients

New Research Supports Safety of Aspirin in Heart Failure

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Large trial comparing it to warfarin finds aspirin not tied to more hospitalizations or deaths
Oral methylprednisolone is associated with increased risk of serious adverse events among patients with immunoglobulin A nephropathy and proteinuria of greater than 1 g/day

Methylprednisolone Ups Adverse Events in IgA Nephropathy

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Recruitment discontinued because of serious adverse events after randomization of 262 patients