PPI Use Linked to Increased Risk of Ischemic Stroke, MI
Risks of first-time stroke, myocardial infarction up especially for long-term users, at high doses
Lifestyle, Metformin Interventions Have Variable Effects
Impact of interventions varies for progression to diabetes, regression to normal glucose regulation
Clinical Evidence Synopsis Published for T2DM
Adding sulfonylurea or metformin to insulin decreases HbA1c about 1%
Oral Antibiotics Cut Risk of SSI in Colorectal CA Resection
Adding antibiotics to mechanical bowel preparation linked to reduced rate of surgical site infection
Extended-Release Naltrexone Promising for Opioid Dependence
Lower use of heroin, other illicit opioids with extended-release naltrexone in superiority analysis
Glycemic Control Up With Oral Semaglutide in Type 2 Diabetes
Phase 3 studies next to assess longer-term/clinical outcomes, safety
Venovenous Hemodiafiltration Improves Metformin Toxicity
Case report describes treatment of female patient who attempted suicide with metformin overdose
Ketamine Not Linked to PTSD in Military Trauma Setting
Only acute stress disorder, total number of surgeries linked to PTSD development in multivariable analysis
Gastric Acid Suppression May Promote Liver Injury
Expansion of intestinal Enterococcus faecalis in mice exacerbates ethanol-induced liver disease
Screening Tools Identify Potentially Inappropriate Meds
However, substantial proportion of PIMS identified in internal medicine ward are not clinically relevant
