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For pregnant women with pre-existing diabetes

Falling Insulin Requirement Linked to Placental Dysfunction

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FIR ≥15 percent linked to increased risk of composite of clinical markers of placental dysfunction
Antidepressant use is common among U.S. individuals aged 12 years and older

Antidepressants Used by 12.7 Percent of Those Age ≥12 in U.S.

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Use is higher among females than males; long-term use for one-fourth of those taking antidepressants
Electrotherapy and acupuncture seem to be beneficial for pain management after total knee arthroplasty

Electrotherapy, Acupuncture Ease Post Knee Arthroplasty Pain

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Meta-analysis shows drop in use of opioids for electrotherapy; delayed opioid use with acupuncture
The U.S. Food and Drug Administration has announced a recall of numerous liquid pharmaceutical products because of possible bacterial contamination that could cause severe infections in vulnerable patients.

FDA: Potential Contamination in Some Liquid Pharma Products

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Concerns over possible bacterial contamination that could cause severe infections in vulnerable patients
The number of opioids prescribed for patients after elective hernia repair can be reduced

Majority of Patients Require Few Opioids After Hernia Repair

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Low opioid analgesic prescribing is achievable for patients undergoing hernia repair
There is a strong relationship between high on-clopidogrel platelet reactivity and two-year ischemic and bleeding outcomes after drug-eluting stent implantation

High Platelet Reactivity Tied to Ischemic, Bleeding Outcomes

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Findings based on two-year follow-up after drug-eluting stent implantation
Many studies used to support U.S. Food and Drug Administration approval of high-risk medical device modifications are not controlled; and efficacy of drugs granted accelerated approval is often confirmed three years after approval

Studies Used for FDA Approval of Device Changes Often Low Quality

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And, efficacy of drugs granted accelerated approval often confirmed only years after approval
Statin prescribing is considerable among nursing home residents

Statin Use Among Nursing Home Residents Varies Significantly

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Between-physician variability accounted for 9.1 percent of unexplained variation in statin use
From 2009 to 2015 there was an increase in opioid overdose admissions requiring intensive care

ICU Admissions for Opioid Overdose Up From 2009 to 2015

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Average annual mortality rate was 7 percent, with increase to 10 percent in 2015
From 2004 to 2014 there was an increase in annual admissions in France for children with unintentional cannabis intoxication

Cannabis Intoxication Admissions in Children Up in France

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Increase in annual admissions for children from 2004 to 2014; 71 percent of patients were ≤18 months