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For patients presenting to the emergency department with acute extremity pain

In ER, Combination of Ibuprofen, Acetaminophen Relieves Pain

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No difference in pain reduction for ibuprofen and acetaminophen vs. 3 opioid/acetaminophen combos
Factors including increases in health care service price and intensity are associated with increases in U.S. health care spending from 1996 to 2013

Increases in U.S. Health Spending Tied to Health Service Price

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Higher spending also linked to population growth and aging, negatively linked to disease incidence
There has been little change in the treatment recommendations for cough due to the common cold since publication of guidelines in 2006

Evidence Scant for Treatment of Cough With the Common Cold

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Update recommends against nonsteroidal anti-inflammatory agents for adults, codeine for children
For patients with Parkinson's disease and excessive daytime sleepiness

Sodium Oxybate Promising for Parkinson’s, Daytime Sleepiness

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Improvements in subjective sleep quality, objectively measured slow-wave sleep duration
Differences in glycosylation between H3N2 egg-adapted vaccines and circulating strains probably reduced vaccine effectiveness during the 2016-2017 influenza season

Glycosylation Differences in Egg-Adapted Vaccines May Cut Impact

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H3N2 egg-adapted vaccines, circulating strains were different in 2016-2017 influenza season
For patients with acute severe bleeding

Delay in Tranexamic Acid Administration Reduces Benefit

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Survival benefit decreases by 10 percent for every 15-minute delay in treatment for severe bleeding
Zelboraf (vemurafenib) has been approved by the U.S. Food and Drug Administration as the first drug to treat certain adults patients with Erdheim-Chester disease.

Zelboraf Approved for Use in Erdheim-Chester Disease

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Kinase inhibitor (vemurafenib) for use in patients with BRAF V600 mutation
For women with ovarian cancer who underwent both surgery and adjuvant chemotherapy

Average Cost of Care in Year After Ovarian Cancer Surgery ~$100K

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Patients bear about 3 percent of these costs in the form of out-of-pocket expenses
For adults older than 50 years

Warfarin Use Linked to Reduced Incidence of Cancer

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Reduced incidence rate ratio in all cancer sites and in prevalent cancer sites among adults aged >50
Among cannabidiol (CBD) products sold online

Cannabidiol Concentration Varies Widely in Online Products

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Of 84 products sampled, 42.85 percent were underlabeled and 26.19 percent were overlabeled