Tofacitinib Superior to Placebo in Active Psoriatic Arthritis
Tofacitinib is superior for patients with inadequate response to TNF inhibitors or conventional DMARDs
Gene Tx Approved for Certain Types of B-Cell Lymphoma
First such treatment for certain types of non-Hodgkin lymphoma
Glycemic Control Up With Oral Semaglutide in Type 2 Diabetes
Phase 3 studies next to assess longer-term/clinical outcomes, safety
No Increased Risks for DOAC Use Versus Warfarin in VTE
Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism
Pre-Exposure Prophylaxis for Homosexual Men Cost-Effective
Introduction of HIV PrEP program cost-effective and possibly cost-saving for men who have sex with men
PPI Use Linked to Increased Risk of Ischemic Stroke, MI
Risks of first-time stroke, myocardial infarction up especially for long-term users, at high doses
Lifestyle, Metformin Interventions Have Variable Effects
Impact of interventions varies for progression to diabetes, regression to normal glucose regulation
Clinical Evidence Synopsis Published for T2DM
Adding sulfonylurea or metformin to insulin decreases HbA1c about 1%
Oral Antibiotics Cut Risk of SSI in Colorectal CA Resection
Adding antibiotics to mechanical bowel preparation linked to reduced rate of surgical site infection
Extended-Release Naltrexone Promising for Opioid Dependence
Lower use of heroin, other illicit opioids with extended-release naltrexone in superiority analysis
