Advertisement
Proton pump inhibitor users have an increased risk of chronic kidney disease or end-stage renal disease

ASN: PPIs Associated With Increased Risk of Kidney Disease

0
Risk for both chronic kidney disease, end-stage renal disease higher with proton pump inhibitor use
For patients with later-stage autosomal dominant polycystic kidney disease

ASN: Tolvaptan Slows eGFR Decline in Later-Stage ADPKD

0
Reduction in decline in eGFR for patients with later-stage autosomal dominant polycystic kidney disease
For patients with rheumatoid arthritis

ACR: Temporary Cessation of MTX Ups Flu Shot Immunogenicity

0
Findings in patients with rheumatoid arthritis taking a stable dose of methotrexate
For patients with rheumatoid arthritis

ACR: Opioids, SSRIs Tied to Higher Fracture Risk in RA

0
Increased risk of osteoporotic fracture with selective serotonin reuptake inhibitors, opioids of any strength
Tezacaftor-ivacaftor or ivacaftor alone is effective for patients with cystic fibrosis who are heterozygous for the Phe508del deletion

Tezacaftor-Ivacaftor, Ivacaftor Alone Effective in CF

0
And tezacaftor-ivacaftor effective for cystic fibrosis patients homozygous for CFTR Phe508del mutation
For patients with rheumatoid arthritis

ACR: Successful Tapering of DMARDs in RA Explored

0
Low level of serum CRP at baseline linked to successful down-titration in multivariate analysis
Patients with a CYP2C19 loss-of-function allele have increased risk of major adverse cardiovascular events with clopidogrel versus alternative antiplatelet therapy after percutaneous coronary intervention

CYP2C19-Genotype Guided Antiplatelet Tx May Be Beneficial

0
MACE risk up with clopidogrel versus alternative therapy for patients with CYP2C19 loss-of-function allele
From 2005 to 2015 there was a decrease in the proportion of infants aged ≤60 days with a urinary tract infection who received four or more days of intravenous antibiotics

Drop in Proportion of Neonates With Long IV Therapy for UTI

0
Decrease from 50 percent in 2005 to 19 percent in 2015; not linked to increase in hospital readmissions
PARP inhibitors demonstrate activity in triple-negative breast cancer tumors without BRCA1/2 mutations

PARP Inhibitors Promising Beyond BRCA1/2 Altered Tumors

0
Talazoparib caused regression in 5 patient-derived xenografts, 4 without germline BRCA1/2 mutations

American College of Allergy, Asthma and Immunology, Oct. 26-30

0
The 2017 Annual Meeting of the American College of Allergy, Asthma & Immunology The annual meeting of the American College of...