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Guidance has been developed for hemoglobin A1c targets for glycemic control among nonpregnant adults with type 2 diabetes; the guidance statement was published online March 6 in the Annals of Internal Medicine.

ACP Updates Guidance for HbA1c Targets for Adults With T2DM

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Clinicians should personalize glycemic control goals; aim for HbA1c of 7 to 8 percent for most adults
Calcium supplements

Calcium ± Vit D Supplements Up Risk of Colon Adenomas, Polyps

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Late effect findings of sessile serrated adenomas, polyps in those taking calcium with/without vitamin D

February 2018 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for February 2018. This roundup includes the latest...
Women with current asthma who use intermittent reliever treatment with short-acting beta-agonists have reduced fertility

Female Infertility Tied to Asthma Managed With Rescue Inhalers

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No link to infertility for those with former asthma, or for those with asthma preventer medications
For individual patients with type 2 diabetes mellitus

Treatment Effect of Fenofibrate Varies in Patients With T2DM

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Treatment effect is greater in patients with dyslipidemia; absolute risk reduction of 2.15 percent
A low risk of serotonin syndrome is seen in association with concomitant use of triptans and selective serotonin reuptake inhibitor or selective norepinephrine reuptake inhibitor antidepressants

Low Risk of Serotonin Syndrome for Triptans + SSRI/SNRI

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Researchers question FDA advisory warning on risk of concomitant use
Trials to evaluate drugs or devices used to treat chronic medical conditions that are published early in the chain of evidence often show an exaggerated treatment effect compared with subsequent trials

Early Studies Often Show Exaggerated Treatment Effect

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Findings based on assessment of trials evaluating drugs, devices to treat chronic medical conditions
For patients with chronic-phase chronic myeloid leukemia

Treatment-Free Remission Feasible After Nilotinib in CML

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For patients with chronic myeloid leukemia in chronic phase, TFR is feasible after second-line treatment
In women with type 2 diabetes

No Link Found for Metformin or Statins and Ovarian Cancer

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Findings based on a Finnish study involving a national cohort of women with type 2 diabetes
Understanding nonadherence in patients and encouraging a change in attitude toward patients and their medication can improve medication adherence

Understanding Rx Nonadherence Can Improve Adherence

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Changing attitudes toward patients and their medication adherence can improve adherence