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For patients with acute severe bleeding

Delay in Tranexamic Acid Administration Reduces Benefit

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Survival benefit decreases by 10 percent for every 15-minute delay in treatment for severe bleeding
Zelboraf (vemurafenib) has been approved by the U.S. Food and Drug Administration as the first drug to treat certain adults patients with Erdheim-Chester disease.

Zelboraf Approved for Use in Erdheim-Chester Disease

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Kinase inhibitor (vemurafenib) for use in patients with BRAF V600 mutation
For women with ovarian cancer who underwent both surgery and adjuvant chemotherapy

Average Cost of Care in Year After Ovarian Cancer Surgery ~$100K

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Patients bear about 3 percent of these costs in the form of out-of-pocket expenses
For adults older than 50 years

Warfarin Use Linked to Reduced Incidence of Cancer

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Reduced incidence rate ratio in all cancer sites and in prevalent cancer sites among adults aged >50
Among cannabidiol (CBD) products sold online

Cannabidiol Concentration Varies Widely in Online Products

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Of 84 products sampled, 42.85 percent were underlabeled and 26.19 percent were overlabeled
Lifestyle modification and medications can reduce the incidence of diabetes in adults at risk

Lifestyle Changes Successfully Reduce Incidence of Diabetes

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Reduced incidence seen with lifestyle changes, meds; however, effect of meds is short-lived
Sertraline treatment does not significantly improve depressive symptoms among patients with non-dialysis-dependent chronic kidney disease and major depressive disorder

Sertraline Treatment No Benefit for Depressive Symptoms in CKD

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No improvement for patients with MDD and chronic kidney disease without dialysis dependence
Most people complete treatment for latent tuberculosis without direct observation

Completion Likely With Self-Administration of TB Treatment

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Self-administration without reminders is noninferior to direct observation in patients with latent TB
Influenza vaccination in the pediatric emergency department setting appears to be a cost-effective strategy

Influenza Vaccines in Pediatric ERs Likely Cost-Effective

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Vaccinating all patients saves $33.51 per flu case averted, averages 27 fewer cases per 1,000 patients
A novel method has been developed to enhance the prevalence estimates of diabetes and prediabetes

Novel Method Developed for Estimating Prevalence of Diabetes

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Authors reweighted surveys, other data sources with population undercoverage to enhance estimates