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Using CYP2C19 genotype-guided dual antiplatelet therapy selection is feasible in a real-world setting

Genotype-Guided Antiplatelet Therapy Feasible, Effective

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Genotype-guided therapy improves outcomes among CYP2C19 intermediate, poor metabolizers
From 2015 to 2016

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

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Of 63,632 drug overdose deaths in 2016, 66.4 percent involved an opioid
Outcomes-based pricing does not reduce the costs of proprotein convertase subtilisin/kexin type 9 inhibitors

Outcomes-Based Pricing Doesn’t Cut Costs of PCSK9 Inhibitors

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Incremental cost-effectiveness ratio for PCSK9 inhibitor improved marginally in three refund scenarios
Older adults believe marijuana to be effective for pain relief

Older Adults Believe Marijuana Can Be Effective for Pain

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Most older adults support its use when recommended by doctor; some support its use for anyone

March 2018 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for March 2018. This roundup includes the latest...
Preoperative chronic opioid use is associated with poor outcomes and continued dependence after posterior lumbar fusion

Pre-Op Chronic Opioid Use Ups Poor Outcomes Post Spinal Fusion

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Preoperative opioid use tied to complications, ER visits, readmission, adverse events, increased costs
The recombinant influenza vaccine is well tolerated in children aged 6 to 17 years

Recombinant Influenza Vaccine Found to Be Safe in Children

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Immunogenicity of RIV4 similar to that of inactivated vaccine, though responses to B Victoria low with both
The use of acid-suppressive medications and antibiotics during the first six months of infancy is tied to subsequent development of allergic disease

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

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Findings for subsequent allergic disease following infant exposure in the first six months of life
A Zika vaccine could substantially prevent future outbreaks through a combination of direct protection and indirect transmission reduction

Zika Vaccine Could Essentially Eliminate Prenatal Infection

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Model shows vaccine is effective through a combo of direct protection, indirect transmission reduction
For patients with stage III colon cancer

3, 6 Month Adjuvant CAPOX Equally Effective for Colon Cancer

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FOLFOX therapy for 6 months had higher disease-free survival rate compared to 3 months of treatment