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Nicotine preloading does not significantly increase subsequent smoking abstinence in adult daily smokers with tobacco dependence

Little Evidence Nicotine Preloading Helps Smokers Quit

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Adjustment for varenicline use as a post-cessation treatment linked to increase in beneficial effect
Youth receiving antipsychotic treatment have adverse changes in adiposity and insulin sensitivity

Antipsychotic Tx Linked to Adiposity Changes in Youths

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Greatest increase in fat with olanzapine; significant decrease in insulin sensitivity in pooled analysis
African-Americans are less likely than whites to be treated with statins or to receive a statin at guideline-recommended intensity

African-Americans Less Likely to Get Recommended Statin Therapy

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Socioeconomic, demographic, belief-related and clinician differences are contributing factors
U.S. officials need to take action to control spiking insulin prices

AMA: Federal Government Must Tackle Rising Insulin Prices

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Agencies should monitor pricing, market competition, and take any necessary enforcement measures
Nearly one-third of patients with primary biliary cholangitis who had had an inadequate response to ursodeoxycholic acid alone achieved a complete biochemical response with the addition of bezafibrate to treatment

Addition of Bezafibrate Beneficial in Primary Biliary Cholangitis

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Complete biochemical response in 31 percent of patients unresponsive to ursodeoxycholic acid alone
Dexmedetomidine prevents excessive γ-aminobutyric acid type A receptor function after anesthesia

Dexmedetomidine Cuts γ-Aminobutyric Acid Receptor Function

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Cuts etomidate-induced increase in α5 γ-aminobutyric acid type A receptor cell-surface expression
Neurologic outcomes in children with diabetic ketoacidosis are similar regardless of the rate of administration or the sodium chloride content of intravenous fluids

IV Fluid Specs Do Not Influence Neuro Outcomes in Kids w/DKA

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Infusion rate, % sodium chloride don't affect neuro outcomes in children with diabetic ketoacidosis
Ambulatory medication reconciliation is associated with lower risk of a composite primary outcome of combined frequency of emergency department visits and hospitalizations over six months

Diabetes Meds Reconciliation May Reduce Risk of ER Visits

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Medication reconciliation linked to lower risk of combined ER visits, hospitalization over six months
Patients with an adverse change in employment after myocardial infarction have increased likelihood of worse outcomes

Adverse Change in Employment Post-MI Tied to Worse Outcomes

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Patients with adverse change in employment more likely to report depression, have lower health status
Risk factors for opioid overdose among hospitalized patients include being age 65 years or older

Older Age, ICU, Poor Renal Fcn Up Risk of Opioid OD in Hospital

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For hospitalized patients, risk also increased for those receiving three or more CNS antidepressants