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May 2018 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for May 2018. This roundup includes the latest...
In postmenopausal women

Postmenopausal Sex Hormone Levels Associated With Later CVD

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Higher testosterone/estradiol ratio linked to elevated risk for incident cardiovascular disease
The likelihood of using antidepressants may be increased for women who have abortions

Abortion Not Tied to Significantly Higher Antidepressant Use

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Risk factors associated with antidepressant use include previous antianxiety, antipsychotic meds
There are considerable gaps in knowledge relating to the effectiveness of non-pharmacologic treatments for attention-deficit/hyperactivity disorder in pediatric patients

Knowledge Gaps Found for Non-Drug Therapy in Peds ADHD

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Review finds no new guidance on comparative effectiveness of these treatments in children, teens
From 2001 to 2016 there was an increase in the number and percentage of opioid-related deaths; in addition

Studies ID Impact of U.S. Opioid-Related Mortality, Rx Patterns

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Burden of deaths up; most patients receiving opioid analgesics use immediate-release formulations
The safety profile of oral propranolol seems to be good for children with infantile hemangioma

Oral Propranolol Seems Safe for Infantile Hemangioma

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Good safety profile for children with infantile hemangioma with no prespecified underlying disease
For patients with episodic migraine

Galcanezumab Beats Placebo for Episodic Migraine

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Treatment with 120- or 240-mg galcanezumab linked to reduction in migraine days versus placebo
The widespread shortages of injectable opioids and small-volume parenteral solutions are jeopardizing patient care and placing a strain on hospital operations

ASHP: SVP, Injectable Opioid Shortages Threaten Patient Care

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98.4 percent of respondents report moderate, severe shortages of morphine, hydromorphone, fentanyl
The data on popular supplements show no consistent cardiovascular benefit

No Consistent Cardiovascular Benefit Seen for Supplements

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Generally moderate- or low-quality evidence for preventive benefits, no effect, or increased risk
Final guidance has been issued by the U.S. Food and Drug Administration to assist in the development of drugs for the prevention of inhalational anthrax for individuals who may have been exposed but who have not yet displayed related signs or symptoms.

FDA Issues Final Guidance on Inhalational Anthrax

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Final guidance designed to assist in development of drugs for prophylaxis of inhalational anthrax