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Compared with intramuscular pethidine

Patient-Directed IV Remifentanil Cuts Epidural Conversions

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Patient-controlled remifentanil reduces proportion of conversions versus intramuscular pethidine
A lawsuit filed Tuesday in California claims that pharmaceutical company AbbVie used cash

California Lawsuit Claims AbbVie Paid Doctors to Prescribe Humira

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Claims physicians prescribed Humira because of financial kickbacks, not as best drug for patient
States may be greatly underestimating the effect of opioid-related overdose deaths because of incomplete cause-of-death reporting

Opioid Deaths 1999 to 2015 May Be Dramatically Underestimated

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Incomplete death certificates led to under-reporting of 70,000 likely opioid deaths
Almost 20 percent of children and adolescents used prescription medications in 2013 to 2014

20% of Children, Adolescents Use Prescription Medications

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8.2 percent of concurrent users of prescription meds at risk for potentially major drug-drug interactions
The most common electronically sent and received types of patient health information include laboratory results and medication lists

Patient Health Information Often Shared Electronically

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Most commonly observed types of PHI sent are referrals, laboratory results, medication lists
Quarterly canakinumab administration is associated with significantly reduced risk for gout attacks without any change in serum uric acid levels

Quarterly Canakinumab Reduces Risk for Gout Attacks

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Doesn't affect serum uric acid levels over time, but targets interleukin-1β
Fourteen percent of older adults hospitalized with non-cardiac conditions are discharged with intensified antihypertensive treatment

HTN Tx Intensification Common Upon Discharge in U.S. Vets

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Fourteen percent of older adults admitted to hospital for non-cardiac conditions had intensification of tx
In 2016 the age-standardized prevalence of insufficient physical activity was 27.5 percent

Global Prevalence of Insufficient Activity 27.5 Percent

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Levels of insufficient physical activity stable between 2001, 2016; increase seen in high-income countries
For high-risk patients with implantable cardioverter-defibrillators (ICDs)

Ranolazine Doesn’t Cut VT, VF, Death in High-Risk ICD Patients

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No significant reduction in VT or VF or death risk for patients with implantable cardioverter-defibrillators
Half of trials on the European Union Clinical Trials Register are non-compliant with the European Commission's requirement that all trials post results to the registry within 12 month of completion

Compliance With Requirement to Report Results on EUCTR Is Poor

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Half of trials on European Union Clinical Trials Register are non-compliant with requirements