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Delayed administration of sodium thiosulfate after cisplatin chemotherapy may prevent treatment-related hearing loss in children with standard-risk hepatoblastoma without affecting survival outcomes

Sodium Thiosulfate Post-Cisplatin May Lessen Hearing Loss

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Children with hepatoblastoma on cisplatin less likely to have hearing loss with sodium thiosulfate added
For children with cystic fibrosis and early Pseudomonas aeruginosa infection

Azithromycin Cuts Pulmonary Exacerbation in CF With Early Pa

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Risk of pulmonary exacerbation down for children with cystic fibrosis, early Pseudomonas aeruginosa
For older adults

Insulin Glargine 300 Safe, Effective in Seniors With T2DM

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Significantly lower annualized rates of documented symptomatic hypoglycemia than Gla-100
Across adult age categories

Cannabis Use Prevalence Up Across Adult Age Groups

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After 2007, overall increase in adjusted odds of daily versus nondaily cannabis use for ages 12 to 64
The U.S. Centers for Disease Control and Prevention and the American Pharmacists Association have created a guide that describes community-clinical linkages

CDC, APhA Create Guide for Community-Clinical Linkages

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Guide details two types of collaborative care models that involve pharmacists, docs working together
For Japanese patients with type 2 diabetes

Aspirin Use Doesn’t Cut Cancer Incidence in Older T2DM Patients

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In subgroup analyses, reduced incidence of cancer seen in participants aged younger than 65 years
Vertical level mergers

Vertical Mergers Could Be Challenging for Primary Care

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Vertical mergers include providers, insurers, retailers, PBMs; may create new model of primary care
There are opportunities for recalibrating the role of opioids in pain care

Coverage Policies Compared for Back Pain Medications

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Utilization management common for opioids; often relies on 30-day limits rather than prior authorization
Pediatric exposure to buprenorphine can result in serious adverse outcomes

Poison Control Center Data Detail Peds Exposure to Buprenorphine

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Children aged <6 have greater odds of hospital admission than teens with single-substance exposure
At the annual meeting of the American Medical Association

AMA: Docs Declare Drug Shortages Public Health Emergency

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AMA calls for greater manufacturer transparency in order to prepare for disasters, mitigate shortages