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Rates of opioid use in the United States do not appear to be declining

U.S. Opioid Use Not Declining, Despite Focus on Abuse

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Higher average daily dose seen in 2017 versus 2007, particularly for the disabled
There was an increase in buprenorphine with naloxone fills in expansion versus nonexpansion counties after Medicaid expansion

Buprenorphine/Naloxone Rx Fills Up With Medicaid Expansion

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Significant increase in buprenorphine with naloxone fills per 100,000 county residents in expansion areas
Artificial intelligence in health care offers opportunities for early detection and triage

Artificial Intelligence Holds Promise in Medicine

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It offers opportunities -- and associated challenges -- for early detection, triage, diagnostics
The demise of the National Guideline Clearinghouse in July 2018 is likely to impact evidence-based health care around the world

Experts Address Loss of the National Guideline Clearinghouse

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Demise of NGC in July 2018 is likely to impact evidence-based health care around the world
U.S. pediatricians and family physicians have considerable knowledge gaps regarding serogroup B meningococcal vaccination

Physicians Lack Knowledge About Serogroup MenB Vaccination

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Primary care docs who are somewhat or not aware of MenB vaccine are less likely to discuss vaccination
Most breast milk samples have measurable Δ-9-tetrahydrocannabinol up to about six days after maternal use

Cannabinoid in Breast Milk Up to Six Days After Marijuana Use

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Predictors of log Δ9-THC concentration include number of hours since last use, number of daily uses
Globally

Alcohol Is Leading Risk Factor for Global Disease Burden

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Alcohol accounted for 2.2 and 6.8 percent of age-standardized female and male deaths in 2016
Four more online networks that operate 21 websites illegally selling potentially dangerous

FDA Warning Letters Target Illegal Online Sales of Opioids

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Medications may be counterfeit, contaminated, expired, or otherwise unsafe
Few participants in clinical trials have strong concerns about the risks of data sharing

Most Research Participants Not Concerned About Data Sharing

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93 percent very or somewhat likely to allow their data to be shared with university scientists
Implementation of a mandatory prescription drug monitoring program does not necessarily reduce the overall rate of opioid prescribing or the mean number of pills prescribed for patients undergoing general surgical procedures

Prescription Drug Monitoring Program May Not Cut Opioid Use

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No significant reduction in percentage of patients prescribed opioids after general surgery