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For adults with type 2 diabetes initiating second-line antidiabetic medications (ADM)

Second-Line Antidiabetic Meds May Impact Cardiovascular Risk

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Cardiovascular risk increased with sulfonylureas and basal insulin versus newer classes of ADM
For patients with knee osteoarthritis and at least 12 months of follow-up

Effect Sizes Uncertain for Meds Versus Placebo in Knee OA

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Meta-analysis: large uncertainty versus placebo for all medications for pain relief
The American College of Obstetricians & Gynecologists has updated its guidance on the management of gestational hypertension and preeclampsia as well as chronic hypertension in pregnant women; the two practice bulletins were published in the January issue of Obstetrics & Gynecology.

ACOG Updates Guidelines for Gestational HTN, Preeclampsia

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Second bulletin provides recommendations for management of chronic hypertension in pregnancy
The American Society of Hematology has developed new guidelines for the treatment of venous thromboembolism; the clinical practice guidelines were recently published in Blood Advances.

ASH Develops Practice Guidelines for Venous Thromboembolism

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Clinical practice guidelines presented for diagnosis, treatment, pediatric and pregnancy-linked VTE
There is considerable variation in opioid prescribing among pediatric patients

Opioid Prescribing Patterns Vary for Pediatric Patients

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Geographic region, race, age, payment method associated with differences in opioid prescribing
The lowest-priced generic drugs are more likely to experience shortages

Low-Priced Generic Drugs Most Likely to Have Shortages

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Shortages associated with modest increases in price, ranging from 6 to 14 percent
More than two-thirds of drug overdose deaths in 2017 involved an opioid

More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids

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Significant increases seen in death rates involving synthetic opioids in 15 of 20 states from 2013 to 2017
The Infectious Diseases Society of America has updated their recommendations for the care of patients with suspected or diagnosed influenza; the clinical practice guidelines were published online Dec. 19 in Clinical Infectious Diseases.

Updated Guidelines Developed for Diagnosing, Treating Influenza

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Rapid molecular assays should be used to improve diagnosis; antivirals should begin as soon as possible
The American Academy of Pediatrics has developed its first guideline for the management of infantile hemangiomas; the clinical practice guideline was published online Dec. 24 in Pediatrics.

New AAP Guideline Available for Infantile Hemangioma Treatment

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Early intervention and/or referral recommended for potentially problematic infantile hemangiomas
Patients with opioid use disorder undergoing cardiac surgery have increased complications and costs

Complications, Costs Up With Cardiac Sx in Opioid Use Disorder

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No increased risk of mortality, but increase in incidence of major complications