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The use of herbal medicinal products during pregnancy and the postnatal period is associated with increased risk of adverse events

Review Links Adverse Events to Use of Herbal Meds in Pregnancy

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Increased odds of preterm birth with almond oil; oral raspberry leaf linked to cesarean delivery
Use of the orally administered β-site amyloid precursor protein-cleaving enzyme 1 inhibitors

Verubecestat, Atabecestat Not Beneficial for Preventing Alzheimer Disease

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Two trials show lack of effectiveness versus placebo for preclinical Alzheimer disease
Because of the danger of "serious harm" to patients

FDA: Patients Should Not Abruptly Stop Taking a Prescribed Opioid

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Agency warns that rapid discontinuation can result in uncontrolled pain or withdrawal symptoms
Continued smoking among patients with cancer and the associated increase in attributable first-line cancer treatment failure is tied to significant incremental costs for subsequent cancer treatments

Continued Smoking Among Cancer Patients Ups Costs by $3.4B

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Estimates based on additional treatment following higher failure risk for first-line cancer treatment
For older nursing home residents

More Secondary Prevention Meds May Reduce Deaths After AMI

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Mortality lower with more meds for older nursing home residents after acute myocardial infarction
Chloroprocaine results in adequate anesthesia with quick recovery of sensory/motor functions for knee arthroscopy in the ambulatory setting

Chloroprocaine Offers Adequate Anesthesia for Knee Arthroscopy

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Shorter time to complete recovery from motor blockade seen for chloroprocaine compared with prilocaine
Greater practice restrictions are associated with a lower percentage of nurse practitioners with waivers to prescribe buprenorphine

Many NPs Unable to Prescribe Meds to Treat Opioid Addiction

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Greater practice restrictions lead to lower percentage of NPs with waivers to prescribe buprenorphine
Evenity (romosozumab-aqqg) was approved for the treatment of osteoporosis in postmenopausal women with a high risk for fracture

FDA Approves Osteoporosis Tx for High-Risk Postmenopausal Women

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Boxed warning states increased risks for cardiovascular death, stroke, heart attack
For people with hepatitis C virus who inject drugs and receive opioid agonist therapy

High Response Seen for All Hep C Tx Models in Injection Drug Users

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Directly observed therapy tied to greater adherence than self-administered individual treatment
For U.S. adults

Dietary Supplement Use Not Linked to Mortality Benefits

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Excess calcium intake may increase risk for cancer death; link related to supplemental calcium intake