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Vitamin D supplementation safely and substantially reduces the rate of moderate-to-severe chronic obstructive pulmonary disease exacerbations in patients with baseline 25-hydroxyvitamin D levels <25 nmol/L

Vitamin D Supplementation Can Help Cut COPD Exacerbations

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Review shows supplementation only effective for baseline vitamin D levels <25 nmol/L
A new clinical guideline from the American Gastroenterological Association published Dec. 18 in Gastroenterology focuses on the medical management of patients with mild-to-moderate ulcerative colitis.

Guideline Issued for Treatment of Mild/Moderate Ulcerative Colitis

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Standard-dose mesalamine or diazo-bonded 5-ASA recommended versus low-dose mesalamine
For the first time in history

Opioids Now More Deadly for Americans Than Traffic Accidents

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Preventable injuries are the third leading cause of death in the United States
The U.S. Preventive Services Task Force recommends risk-reducing medications for women at high risk for breast cancer who are at low risk for adverse events

USPSTF Recommends Risk-Reducing Meds for Breast Cancer

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Risk-reducing medications recommended for women at high risk, not for routine use
The median overall survival from diagnosis for patients with stage IV anaplastic lymphoma kinase-positive non-small cell lung cancer is 6.8 years

Median Survival for Stage 4 ALK-Positive NSCLC Nearly 7 Years

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Most patients in study received crizotinib; prognosis worse when more organs have tumors at diagnosis
The Women's Health Initiative recommendations for menopausal hormone therapy use issued in 2002 have been widely adopted

Menopausal Hormone Tx Use Down Post-WHI Recommendations

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But large declines seen in subgroups for whom MHT is recommended, including younger women
Topical application of a transient receptor potential vanilloid subfamily

Investigational Cream Promising for Atopic Dermatitis

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In phase IIb trial, success rates were higher with TRPV1 antagonist than with vehicle cream
Eighteen percent of patients with back pain experience a persistent trajectory

One in Five Back Pain Patients Experience Persistent Pain

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Significant differences seen in patterns of medication, health care use across back pain trajectories
The introduction of emergency department- or community-based pharmacists with an expanded scope of practice may cut emergency department overcrowding

Expanding Pharmacist Practice Scope Could Reduce ED Overcrowding

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Benefits could be seen for frequent complaints like cough, dermatitis, and inflammation of ear, nose, throat
The Substance Abuse and Mental Health Services Administration national helpline (800-662-HELP) seems to be underappreciated in the media and by the general population

800-662-HELP Underappreciated in Media, General Population

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Searches for SAMHSA hotline did not increase after singer Demi Lovato's heroin-related overdose