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Potential antidepressant overprescribing appears to be common among elderly patients and involves mostly newer antidepressants used for nonspecific psychiatric symptoms and subthreshold diagnoses

Antidepressant Overprescribing Appears Common in Elderly

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Overprescribing tied to newer antidepressants, non-face-to-face interactions with prescribers
Treatment of psoriasis with biologic therapy is associated with a reduction in noncalcified coronary plaque and improved plaque morphology

Psoriasis Tx Linked to Drop in Noncalcified Coronary Plaque

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Noncalcified plaque burden and necrotic core reduced in association with biologic therapy
Implementation of a novel enhanced recovery after surgery protocol can reduce patients' postoperative opioid requirements after elective spinal or peripheral nerve surgery

ERAS Protocol Can Cut Opioid Use After Spine Surgery

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Decline seen in postoperative opioid requirements after elective spinal, peripheral nerve surgery
Omadacycline is noninferior to moxifloxacin for community-acquired bacterial pneumonia and noninferior to linezolid for acute bacterial skin infections

Omadacycline Noninferior to Moxifloxacin for Pneumonia

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Second study shows noninferiority to linezolid for acute bacterial skin and skin-structure infections
Recommendations have been updated for tonsillectomy in children; the revised clinical practice guideline was published as a supplement to the February issue of Otolaryngology-Head and Neck Surgery.

Recommendations Updated for Tonsillectomy in Children

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Strong recommendations presented against administering perioperative antibiotics, codeine after tonsillectomy
Cablivi (caplacizumab-yhdp) injection has been approved by the U.S. Food and Drug Administration to treat adults with acquired thrombotic thrombocytopenic purpura.

FDA Approves Cablivi for Rare Blood-Clotting Disorder

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Drug approved to treat adults with acquired thrombotic thrombocytopenic purpura
The 2019 recommended childhood and adolescent immunization schedules have been issued by the American Academy of Pediatrics and published online Feb. 5 in Pediatrics.

AAP Releases 2019 Childhood Immunization Schedules

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Influenza row modified to reflect current recommendations for live attenuated flu vaccine
Compounded topical pain creams are no better than placebo creams for neuropathic pain

Compounded Topical Pain Creams No Better Than Placebo

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At one month, no significant difference seen in positive outcomes for treatment vs. control
Most qualifying conditions for which patients are licensed to use cannabis medically have substantial or conclusive evidence of therapeutic efficacy

Evidence of Therapeutic Efficacy Substantial for Cannabis Use

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Substantial, conclusive evidence of therapeutic efficacy found for 85.5 percent of qualifying conditions
Opioids may be overprescribed to children after orthopedic surgery for supracondylar humerus fractures

After Elbow Surgery, Children May Be Overprescribed Opioids

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Patients who had supracondylar humerus fracture sx used less than 25 percent of prescribed drugs