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Metastasis-free survival is significantly longer among men with nonmetastatic

Darolutamide Slows Spread of Castration-Resistant Prostate Cancer

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Significant survival benefit seen, adverse events similar between darolutamide and placebo
Despite adequate levels of prescriber

Inappropriate Use of Fentanyl Preps Seen Despite Awareness

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Claims data show many prescribed transmucosal immediate-release fentanyl were opioid-nontolerant
For patients with an admitting diagnosis of acute coronary syndrome and/or acute decompensated heart failure

Discharge Opioid Rx for Heart Dz Patients May Impact Follow-Up

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Findings seen in patients with admitting diagnosis of acute coronary syndrome, decompensated heart failure
Age

Risk Factors ID’d for Diffuse Large B-Cell Lymphoma Mortality

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In older patients, risk factors include advanced age, DLBCL stage, Charlson Comorbidity Index
Growth in hospital prices and payments outpaced growth in physician prices and payments from 2007 through 2014

Hospital Prices Growing Faster Than Physician Prices

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Efforts to reduce health care spending should focus on hospital prices
The Tandem Diabetes Care t:Slim X2 insulin pump

FDA Approves First Customizable Insulin Pump

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Product works by delivering insulin under the skin at set or variable rates
Medicare patients with multiple sclerosis face increasing out-of-pocket costs for disease-modifying therapies

Medicare Patients With MS Face Higher Out-of-Pocket Rx Costs

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Projected cumulative out-of-pocket spending for disease-modifying therapies for 2019 was $6,894
For denosumab-treated women with postmenopausal osteoporosis

Rates of Osteonecrosis of the Jaw Low for Denosumab-Treated Women

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Invasive oral procedures associated with increased incidence of ONJ, but rate low overall
Achieving high serogroup B meningococcal vaccination coverage is recommended following university-based outbreaks of meningococcal disease caused by serogroup B

High Rates of MenB Vaccination Advised in University Outbreaks

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Estimated first-dose vaccination coverage varied from 14 to 98 percent in 10 university outbreaks
The 2018 to 2019 influenza season has been low in severity so far

CDC: Severity of Influenza Season Low Through Feb. 2, 2019

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Vaccine effectiveness 47 percent against all flu virus infection associated with acute respiratory illness