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In children aged younger than 19 years

Suicide Attempts by Self-Poisoning Have Increased in Teens

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Increase from 2011 to 2018 among children aged 10 to 18 years mainly driven by girls
Isradipine does not appear to slow progression of disability in patients with de novo Parkinson disease

AAN: Isradipine Offers No Benefit in Parkinson Disease

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No significant treatment effect seen in UPDRS Part I to III score measured in the ON state
Only state naloxone access laws allowing direct dispensing of naloxone by pharmacists appear to be useful in cutting fatal overdose rates

Fatal Overdoses Reduced With Pharmacist Dispensation of Naloxone

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However, greater naloxone availability tied to more nonfatal overdoses seen in emergency departments
For patients with aquaporin-4-immunoglobulin G-positive neuromyelitis optica spectrum disorder

AAN: Eculizumab Reduces Risk for Relapse in Neuromyelitis Optica

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But no significant between-group difference noted in measures of disability progression
Health professionals are generally supportive of medicinal cannabis use but report a lack of knowledge about its use

Health Professionals Supportive of Medicinal Cannabis

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However, across medicine, pharmacy, and nursing, providers need more information
Statin use may lower the risk for primary open-angle glaucoma

Longer Duration of Statin Use Linked to Lower Risk for Glaucoma

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Self-reported high cholesterol levels without statin use tied to higher glaucoma risk
For women with bleeding in early pregnancy

Progesterone Offers No Benefit for Bleeding in Early Pregnancy

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Progesterone administered in first trimester does not result in significantly more live births
The use of alteplase between 4.5 and 9.0 hours after stroke onset results in a higher number of patients with no or minor neurological deficits

Alteplase Seems Beneficial at 4.5 to 9.0 Hours After Stroke

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Trial terminated because of loss of equipoise after publication of positive results from previous trial
In 2018

CDC: Uninsurance Levels Did Not Change Significantly in 2018

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Uninsurance increased among adults aged 45 to 64 years; increase seen in high-deductible health plans
An estimated 15.0 million patients will require first-course chemotherapy in 2040

Fifteen Million Patients Will Need First-Course Chemo in 2040

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Number of cancer physicians required to deliver optimal chemo set to increase to 100,000 by 2040