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Type 1 diabetes diagnosed in those older than age 30 years is clinically and biologically similar to disease occurring at younger ages but is often misidentified

Late-Onset Type 1 Diabetes Often Misdiagnosed as Type 2

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Almost one-third of people older than 30 when first diagnosed with type 2 diabetes have type 1
A single dose of a prophylactic antibiotic is beneficial after operative vaginal birth and reduces the risk for confirmed or suspected maternal infection

Prophylactic Antibiotic Cuts Infection Risk After Operative Vaginal Birth

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Benefits seen following operative vaginal birth at 36 weeks of gestation or later
The selective Bruton's tyrosine kinase inhibitor evobrutinib at a dose of 75 mg once daily is associated with fewer enhancing lesions during weeks 12 through 24 among patients with relapsing multiple sclerosis

AAN: Oral BTK Inhibitor Superior to Placebo in Multiple Sclerosis

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Fewer enhancing lesions seen in weeks 12 to 24 for 75 mg evobrutinib once daily versus placebo
A prognostic model can predict the risk for seizures in pregnant women with epilepsy on medication

Tool Predicts Seizure Risk During, After Pregnancy

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Risk for seizures predicted for pregnant women with epilepsy on medication
Fournier gangrene is a safety concern for adults with diabetes receiving treatment with sodium-glucose cotransporter-2 inhibitors

Fournier Gangrene Is Safety Concern With SGLT2 Inhibitors

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FDA identified 55 cases of FG in patients on SGLT2 inhibitors from March 2013 through January 2019
For patients with psoriasis treated with systemic medications

Infection Risk Lower With Certain Psoriasis Treatments

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Risk for serious infection reduced for new users of apremilast, etanercept, ustekinumab versus methotrexate
For internal medicine residents

Prior Training Increases Internists’ Knowledge of PrEP for HIV

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IM residents with training report more frequent prescribing, higher comfort level in educating patients
When pharmacies close

Heart Patients at Risk When Pharmacies Close

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Study shows link between pharmacy closures and medication noncompliance among patients with CVD
In children aged younger than 19 years

Suicide Attempts by Self-Poisoning Have Increased in Teens

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Increase from 2011 to 2018 among children aged 10 to 18 years mainly driven by girls
Isradipine does not appear to slow progression of disability in patients with de novo Parkinson disease

AAN: Isradipine Offers No Benefit in Parkinson Disease

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No significant treatment effect seen in UPDRS Part I to III score measured in the ON state