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Esketamine nasal spray plus an oral antidepressant appears to be a safe and effective treatment for patients with treatment-resistant depression

Esketamine Nasal Spray May Improve Refractory Depression Outcomes

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Findings seen among outpatients with treatment-resistant depression using combo nasal spray, oral antidepressant
The rate of emergency department visits with opioids only given during the visit is higher than the rate for visits with opioids only prescribed at discharge and for visits with opioids given and prescribed

More Opioids Given Than Prescribed in Emergency Department

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Opioids more often given in ED than prescribed at discharge for adult ED visits
The International Pediatric Multiple Sclerosis Study Group has updated standards for future clinical trials in pediatric multiple sclerosis; the new recommendations were published in the May 28 issue of Neurology.

Recommendations Developed for Pediatric Multiple Sclerosis Trials

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Biological rationale exists for using treatments proven efficacious in adults with MS for pediatric MS
The proportion of prescriptions for opioids written by dentists in the United States was 37 times greater than the proportion of opioid prescriptions written by English dentists in 2016

U.S. Dentists Prescribe Opioids More Often Than U.K. Dentists

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Dentists in the United States also prescribe a greater range of opioids, including long-acting opioids
For high-risk and older patients with previously untreated chronic lymphocytic leukemia

Ibrutinib, Venetoclax Active in High-Risk, Seniors With CLL

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Findings seen in phase 2 study of combo regimen for first-line treatment of chronic lymphocytic leukemia
The first test to detect the Zika virus in human blood has been approved by the U.S. Food and Drug Administration.

FDA Approves First Test for Zika in Human Blood

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The ZIKV Detect 2.0 IgM Capture ELISA is made by Seattle-based InBios
Potentially inappropriate prescribing is tied to increased health care utilization and poor outcomes among older individuals seen in primary care practices

Inappropriate Prescribing Leads to Poor Outcomes in Older Adults

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Potentially inappropriate prescribing tied to ED visits, adverse drug events, functional decline
Reading clinical notes can help patients to understand why medications are prescribed and improves medication adherence for some patients

Reading Visit Notes May Improve Medication Management

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Patients say note reading helps them understand why meds are prescribed, makes them feel in control
For patients with newly diagnosed multiple myeloma

Daratumumab Cuts Risk for Progression in Multiple Myeloma

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Adding daratumumab to lenalidomide + dexamethasone beneficial for newly diagnosed multiple myeloma
The prevalence of diagnosed diabetes has plateaued during the last eight years

Recent Plateauing Seen in Prevalence of Diagnosed Diabetes

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Following increase from 1990 to 2007, incidence rates significantly decreased since 2007