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Opioids do not provide improved pain control following a vasectomy and may be tied to a higher risk for persistent use

Opioids May Not Be Needed for Acute Pain Control After Vasectomy

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Initially prescribed opioids have higher rate of persistent use but no acute improved pain control
Topical supplemental testosterone increases running performance and lean body mass in young

Boosting Testosterone Ups Women’s Athletic Performance

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Authors say findings have implications for classification in international sporting competitions
The U.S. opioid epidemic cost the nation's economy $631 billion from 2015 through 2018

Opioid Crisis Cost United States $631 Billion Over Four Years

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Cost of opioid epidemic this year likely to be between $171 billion and $214 billion
Initiation of statin therapy during childhood in patients with familial hypercholesterolemia slows the progression of carotid intima-media thickness and reduces the risk for cardiovascular disease over 20 years

Statins in Childhood Aid Familial Hypercholesteremia Outcomes

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Patients show slowed progression of carotid intima-media thickness, lower risk for cardiovascular disease
The postoperative risk for pulmonary embolism extends more than six weeks for six types of surgery

Pulmonary Embolism Risk Elevated for More Than Six Weeks Postop

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Findings based on six common surgery types in large French study
In thrombotic antiphospholipid antibody syndrome

Study Compares Anticoagulants for Antiphospholipid Syndrome

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Authors find rivaroxaban not noninferior to vitamin K antagonists for secondary thromboprophylaxis
Most dimensions of quality of life (QoL) are impaired in patients with relapsed/refractory multiple myeloma

Effects on Quality of Life Mixed for Tx of Multiple Myeloma

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Reduced pain but worsening of neuropathy seen for IxaThalDex induction tx in relapsed/refractory MM
Ibrutinib is associated with an increased risk for new or worsened hypertension in patients treated for B-cell malignancies

Ibrutinib Therapy Linked to New, Worsened Hypertension

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Ibrutinib-related hypertension associated with increased risk for major adverse cardiovascular events
Clinical recommendations for the prevention of secondary fractures among older adults with hip or vertebral fracture have been issued by a multi-stakeholder coalition assembled by the American Society for Bone and Mineral Research and published online Sept. 20 in the Journal of Bone and Mineral Research.

Recommendations Developed for Preventing Secondary Fractures

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Coalition reaches consensus on guidance for patients 65 years and older with hip or vertebral fracture
After one year of therapy with lumacaftor-ivacaftor in a real-world setting

Lumacaftor-Ivacaftor Aids Cystic Fibrosis in Real-World Setting

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Improved lung function, increased BMI, reduced need for IV antibiotics seen after one year of therapy