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Among patients hospitalized for acute coronary syndrome

High-Intensity Lipid Lowering May Aid Very Elderly After ACS

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Benefit of simvastatin-ezetimibe combo after acute coronary syndrome greatest for patients ≥75 years
Overuse of broad-spectrum antibiotics is associated with increased mortality and other poor outcomes in adults admitted for community-onset pneumonia

Poor Pneumonia Outcomes Tied to Overuse of Broad-Spectrum Antibiotics

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Poor outcomes include higher mortality, longer hospital stay, and greater risk for C. difficile infection
From 2012 to 2018

2012 to 2018 Saw Substantial Rise in Naloxone Dispensing

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Regional variation in naloxone dispensing considerable; rates lowest in most rural counties
Women with premature ovarian insufficiency receiving hormone therapy have poor sleep quality

Premature Ovarian Insufficiency Tied to Poor Sleep Quality

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Patients take longer to fall asleep, use more sleep aids, have more fatigue
Efpeglenatide once weekly leads to dose-dependent reductions in glucose and body weight in patients with early type 2 diabetes

Study Explores Dose Ranges for Efpeglenatide in Early T2DM

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Safety profile consistent with other long-acting glucagon-like peptide 1 receptor agonists
In 2017

Age-Adjusted Drug Overdose Death Rate Higher in Urban Counties

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Rates of age-adjusted death higher in urban counties for men; higher in rural counties for women
Hormone therapy formulations have differential effects on heart fat deposits in early menopausal women

Estrogen Preps Differ in Effects on Heart Fat Deposits

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Increase in epicardial adipose tissue less likely with oral conjugated equine estrogens in early menopause
For elderly patients taking statins for primary prevention

Discontinuing Statins Linked to Cardiac Admissions in Elderly

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Admission risk for any cardiovascular event up with discontinuation among previously adherent seniors
Brand-brand competition in the U.S. pharmaceutical market has not lowered drug list prices

Brand-Brand Competition Has Not Cut Prices in Pharma Market

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Review shows evidence that brand-brand competition was mediated by quality of competing drugs
For adolescents with perinatally acquired HIV

Compliance With Meds Falters With Age in Youth Born With HIV

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Prevalence of nonadherence increased from preadolescence to late adolescence/young adulthood