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Implementation of a policy that eliminated nonmedical exemptions from school entry requirements correlated with an increase in vaccination coverage and a reduction in nonmedical exemptions in California

Vaccination Rates Improved With Removal of Nonmedical Exemptions

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In California, MMR coverage increased in postpolicy period, while nonmedical exemptions decreased
New warnings about the risk for dangerous breathing difficulties when gabapentinoids are used with opioids or by certain patients must now appear on product labels

Gabapentinoids, Opioids Combo Carries Risk for Breathing Problems

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Serious breathing problems can occur in patients who use gabapentinoids with opioids or other CNS depressants
For patients with metastatic colorectal cancer

Continuing Full Induction Regimen Not Beneficial in Metastatic CRC

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Maintenance therapy shows benefit versus observation in terms of PFS but not overall survival
For patients with systemic lupus erythematosus

Anifrolumab Improves Response at 52 Weeks in Lupus

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Rate of composite response showing reduced disease activity higher with anifrolumab versus placebo
The first Ebola vaccine approved by the U.S. Food and Drug Administration is a single-dose injection called Ervebo. The vaccine from Merck & Co. is approved to protect against the Zaire ebolavirus in people ages 18 years and older.

FDA Gives First Ebola Vaccine for Adults the Green Light

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Ervebo shown to be highly effective in preventing infection in people exposed to the virus
The rate of opioid-related suicides as well as unintentional deaths significantly increased from 2000 to 2017

Opioid-Related Suicides Down, Rate of Unintentional Deaths Up

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Crises of opioid overdose deaths and suicide do not appear closely linked
Misuse/abuse

Misuse of Nonopioid Medications Appears to Be on the Rise in U.S.

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Increases seen for misuse/abuse, suicide attempts, and hospitalizations linked to gabapentin, baclofen
For pregnant women with HIV

Antiretroviral Prescribing in Pregnancy Strays From National Guidelines

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Many prescribed ARVs with insufficient evidence, not recommended for use in pregnant women with HIV
Cannabis use is increasing rapidly among people with depression

Cannabis Use Up, Especially Among Those With Depression

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Study also shows declining perception of cannabis use-related risks
Compared with placebo

Addition of Maintenance Olaparib Slows Advanced Ovarian Cancer

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Benefit substantial for homologous-recombination deficiency positive tumors with, without BRCA mutations