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The rate of religious exemptions for vaccination among kindergartners is associated with the availability of personal belief exemptions

Religious Exemption Rate for Vaccination Up in 2017 to 2018

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Number of religious exemptions increased after personal belief exemption eliminated in Vermont
For patients with cystic fibrosis with Phe508del-minimal function genotypes

Elexacaftor-Tezacaftor-Ivacaftor Efficacious for Cystic Fibrosis

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Percentage of FEV1 higher at four weeks and through 24 weeks with treatment versus placebo
Adalimumab exposure in pregnancy does not increase the risk for birth defects

Risk for Birth Defects Not Increased With Adalimumab

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Risk for preterm delivery higher in women with RA, Crohn disease regardless of adalimumab exposure
Most estimates show no differences in effectiveness between classes of antihypertensive agents

Equivalence Seen Between Drug Classes for HTN Monotherapy

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Thiazide, thiazide-like diuretics superior to ACEi; nondihydropyridine calcium channel blockers inferior
From 2015 to 2017

Increase Seen in Opioid-, Synthetic Opioid-Involved OD Deaths

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From 2015 to 2017, number of opioid-involved overdose deaths increased for nearly all racial/ethnic groups
Patients undergoing corneal surgery and receiving fewer opioid tablets still have adequate pain control

Pain Control Adequate With Fewer Opioids After Corneal Surgery

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After assessment of postoperative opioid use, patients receive fewer opioid tablets but pain is controlled

October 2019 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for October 2019. This roundup includes the latest...
Makena

FDA Committee: Makena Should Be Removed From Market

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Drug was approved by FDA in 2011 to reduce risk for preterm birth in at-risk women
For relapsed or refractory acute myeloid leukemia with mutations in the FMS-like tyrosine kinase 3 gene (FLT3)

Gilteritinib Superior in Relapsed, Refractory FLT3-Mutated AML

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Overall survival significantly longer, percentage of remission higher than with salvage chemotherapy
Patients receiving checkpoint inhibitor therapy often have acute kidney injury

Acute Kidney Injury Often Seen With Checkpoint Inhibitor Use

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8 percent of patients receiving checkpoint inhibitor therapy experienced sustained acute kidney injury