Opioid-Related Suicides Down, Rate of Unintentional Deaths Up
Crises of opioid overdose deaths and suicide do not appear closely linked
Misuse of Nonopioid Medications Appears to Be on the Rise in U.S.
Increases seen for misuse/abuse, suicide attempts, and hospitalizations linked to gabapentin, baclofen
Antiretroviral Prescribing in Pregnancy Strays From National Guidelines
Many prescribed ARVs with insufficient evidence, not recommended for use in pregnant women with HIV
Cannabis Use Up, Especially Among Those With Depression
Study also shows declining perception of cannabis use-related risks
Addition of Maintenance Olaparib Slows Advanced Ovarian Cancer
Benefit substantial for homologous-recombination deficiency positive tumors with, without BRCA mutations
Fenfluramine Reduces Convulsive Seizures in Dravet Syndrome
Drop in monthly frequency of convulsive seizures significantly greater with fenfluramine versus placebo
FDA to Allow States to Import Prescription Drugs From Other Countries
All imports would have to be FDA-approved, tested to ensure quality, relabeled to meet U.S. labeling requirements
SABCS: Anastrozole Tied to Lasting Reduction in Breast Cancer Risk
Breast cancer risk significantly lower at median follow-up of 131 months; effect continued after treatment
Benzodiazepines With Opioid Agonist Tx May Up Mortality Risk
Coprescription of z-drugs with OAT also linked to increased risk for drug-related poisoning mortality
One in 10 Hospital Patients May Carry C. Diff at Admission
Asymptomatic carriers of C. difficile at significant risk for progression to symptomatic infection
