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Amongpatients with multidrug-resistant HIV-1 infection who have limited therapy options

Fostemsavir Active in Multidrug-Resistant HIV-1 Infection

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Reduction in HIV-1 RNA level significantly greater for fostemsavir versus placebo in randomized cohort
For patients with transfusion-dependent β-thalassemia

Reduction Noted in Transfusion Burden With Luspatercept

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Reduction seen with luspatercept versus placebo for patients with transfusion-dependent β-thalassemia
Following severe criticism

Gilead Backs Down on Special Designation for Possible COVID-19 Drug

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Pharmaceutical company had asked the FDA to designate remdesivir an 'orphan drug'
The National Institutes of Health has launched a new website with educational resources for hospital employees

Workers at Risk for COVID-19 Exposure Can Access Online Training

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The National Institute of Environmental Health Sciences launched virtual training website to protect workers
For women with early breast cancer receiving anthracyclines or trastuzumab

ACC: Statins Cut Heart Failure Risk in Early Breast Cancer Treatment

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Risk for heart failure hospital visit declined with statins for women receiving anthracyclines, trastuzumab
Proton pump inhibitor use in children is associated with a small but significant increased risk for any fracture

Proton Pump Inhibitors May Up Fracture Risk in Children

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Small but significant risk seen for upper-limb and lower-limb fractures
One in 10 older adults hospitalized for common medical conditions are discharged with intensified diabetes medications

Many Older Adults Receive Inpatient Diabetes Rx Intensification

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Benefit unlikely in half due to limited life expectancy or already being at their HbA1c goal
National health expenditures are projected to increase at an average annual rate of 5.4 percent for 2019 to 2028

National Health Spending Expected to Increase Through 2028

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National health expenditures expected to represent 19.7 percent of gross domestic product by 2028
Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions

FDA Warns of Defective EpiPen Dangers

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Devices may activate prematurely if the blue safety release is removed using sideways force
For relatively healthy older individuals

Daily Low-Dose Aspirin Does Not Cut Dementia Risk in Seniors

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Risks for dementia, probable Alzheimer disease, MCI not reduced by low-dose aspirin versus placebo