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A deal for hundreds of millions of syringes that could be used to quickly administer a possible vaccine against COVID-19 has been reached between the U.S. government and a private company.

Plan in Place to Up Production of Prefilled Syringes for Future COVID-19 Vaccine

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Project Jumpstart aims to produce 100 million prefilled syringes by the end of 2020 and more than 500 million in 2021
Atezolizumab plus bevacizumab improves survival outcomes versus sorafenib in patients with unresectable hepatocellular carcinoma

Atezolizumab-Bevacizumab Beats Sorafenib in Liver Cancer

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Overall, progression-free survival longer with combo in unresectable hepatocellular carcinoma
For women with bacterial vaginosis

Live Biotherapeutic Promising for Prevention of Bacterial Vaginosis

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Following vaginal metronidazole for BV, incidence of recurrence lower with Lactin-V versus placebo
For pediatric patients with acute myeloid leukemia

Dexrazoxane Preserves Cardiac Function in Pediatric Leukemia

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Beneficial for patients with AML receiving anthracyclines, with no impact on event-free, overall survival
Among patients with heart failure

For Those With Heart Failure, ACE2 Concentrations Up in Men

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Use of ACE inhibitors, ARBs not tied to higher plasma ACE2 concentrations in those with heart failure
After the COVID-19 emergency declarations

Pediatric Vaccine Ordering Has Decreased During COVID-19

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Decrease seen in VFC-funded APIC-recommended childhood vaccines after national emergency declaration
There is a crude correlation between vitamin D levels and the number of COVID-19 cases and COVID-19 mortality

Crude Link ID’d for Vitamin D Levels, COVID-19 Cases, Death

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Vitamin D levels severely low in aging population, the most vulnerable population to COVID-19
High-dose anakinra

Anakinra May Reduce Systemic Inflammation in COVID-19

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At 21 days, survival was 90 percent in anakinra group versus 56 percent in standard treatment group
For patients with COVID-19

Triple Antiviral Therapy Promising for Mild-to-Moderate COVID-19

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Duration of viral shedding shorter with combination of lopinavir-ritonavir, ribavarin, interferon beta-1b
The presence of a residual shunt after patent foramen ovale closure is associated with an increased risk for recurrent stroke or transient ischemic attack

Residual Shunt After PFO Closure Linked to Higher Risk for Stroke

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Risk for recurrent stroke, transient ischemic attack increased with presence of residual shunt