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In a clinical report from the American Academy of Pediatrics

Guidelines Issued on Managing Infants Exposed to HIV

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Counseling should be provided for parents, caregivers of infants exposed to HIV, including for routine care
Long-term survival analysis shows that patients with earlier initiation of sodium phenylbutyrate-taurursodiol treatment for amyotrophic lateral sclerosis have longer median overall survival

Investigational Drug May Prolong Survival in Patients With ALS

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Median survival 6.5 months longer with initiation of PB-TURSO treatment compared with placebo
Most users report taking cannabidiol as a therapeutic for diagnosable health conditions

Most Users Report Cannabidiol Use for Treatment of Diagnosable Conditions

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Psychiatric, orthopedic, and sleep issues most commonly cited in a Reddit forum
An inactivated severe acute respiratory syndrome coronavirus 2 vaccine seems safe and induces humoral responses

Inactivated SARS-CoV-2 Vaccine Well Tolerated in Phase 1/2 Trial

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Neutralizing antibody geometric mean titers higher in vaccine group at day 42 in phase 1 trial
For about 20 percent of patients with neovascular age-related macular degeneration

Anti-VEGF Therapy May Aid Visual Acuity in Some nAMD Patients

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Useful visual acuity preserved for about 20 percent of patients over their average remaining lifetime
Pfizer will not apply for emergency authorization of its COVID-19 vaccine before the third week in November

No Pfizer COVID-19 Vaccine Expected Before Election

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Company has reversed its previous claims that it would apply for the approval in October
Upadacitinib is superior to abatacept for patients with rheumatoid arthritis refractory to biologic disease-modifying antirheumatic drugs

Upadacitinib Tops Abatacept for RA Refractory to DMARDs

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Superior for mean change in composite DAS28-CRP values and remission, but more adverse events seen
Manualized psychotherapy interventions combined with pharmacotherapy seem beneficial for bipolar disorder

Pharmacotherapy, Psychotherapy Combo Best for Bipolar Disorder

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Manualized treatments linked to significantly reduced recurrence rates versus control treatments
Women who experience their first myocardial infarction at ≤50 years of age are less likely than men to undergo coronary revascularization or be treated with guideline-directed medical therapies

Outcomes Worse for Women With MI at 50 Years or Younger

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Women less likely to undergo coronary revascularization, receive guideline-directed medical treatment
The U.S. Food and Drug Administration is requiring labeling changes to nonsteroidal anti-inflammatory drugs that warn of the risks of taking these drugs at 20 weeks of pregnancy or later

FDA Requiring Labeling Changes to NSAIDs Warning of Risks in Pregnancy

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Labeling must indicate risks to unborn baby with NSAID use at 20 weeks of pregnancy or later