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New cannabinoid use is associated with elevated rates of adverse outcomes among older adults with chronic obstructive pulmonary disease

Cannabinoid Use Tied to Adverse Outcomes With COPD

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In older adults with COPD, cannabinoid use tied to all-cause mortality, hospitalizations
Polypharmacy

Polypharmacy Common in Seniors With Heart Failure

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With increasing number of medications, more rapid increase seen in number of noncardiovascular meds
Enrollment in a study testing an experimental antibody therapy against COVID-19 has been paused by independent monitors.

COVID-19 Antibody Treatment Study Paused

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ACTIV-3 study, testing use of an antibody therapy with remdesivir, paused 'out of an abundance of caution'
Tranexamic acid given in the prehospital setting to injured patients at risk for hemorrhage does not lower 30-day mortality

ACS: Tranexamic Acid No Better Than Placebo After Severe Injury

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Antifibrinolytic agent may lower 30-day mortality when used within one hour of injury, for severe shock
A study to assess whether certain approved or experimental drugs are effective against COVID-19 and warrant testing in large clinical trials has been launched by the U.S. National Institutes of Health (NIH).

NIH Launches Trial of Antibody Drugs Against COVID-19

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The phase 2 trial will assess effectiveness of monoclonal antibodies in conjunction with remdesivir
By treating or preventing infection

Glecaprevir and Pibrentasvir Aid HCV D&#43/R− Kidney Transplants

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Two studies demonstrate safe transplant of kidneys from deceased donors with HCV infection
Sitagliptin treatment added to standard care is associated with reduced mortality and improved clinical outcomes for patients with type 2 diabetes hospitalized with COVID-19

Sitagliptin May Cut Mortality in T2DM Patients With COVID-19

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Sitagliptin at time of hospitalization linked to reduced mortality, improved clinical outcomes
Warning letters have been sent to five companies for illegally selling dietary supplements that contain cesium chloride

FDA Warns Companies About Illegal Sales of Dietary Supplements

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The supplements contain cesium chloride, but no cesium chloride-containing products are FDA-approved
Evidence-based guidelines successfully reduce postoperative opioid prescribing without increased refill rates

One Size May Not Fit All for Postoperative Opioid Prescribing

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Guidelines reduce postoperative opioid prescribing but may result in inadequate pain control for some
More than half of patients offered participation in cancer clinical trials are willing to participate

More Than Half of Cancer Patients Willing to Enroll in Clinical Trials

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Participation rates similar for Black and White patients, treatment and cancer control trials