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Oxcarbazepine Tied to Nontrauma Fracture in Children Aged 4 to 13 With Epilepsy

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Initiating oxcarbazepine, but not levetiracetam, linked to increased incidence rate ratio for nontrauma fracture

Traumatic Brain Injury Tied to Later Opioid Use, Misuse

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History of TBI tied to 52 percent increased odds of prescription opioid use, 65 percent increased odds of prescription opioid misuse

Uptake Low for Monoclonal Antibodies for COVID-19

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Use peaked in January and declined in early 2021, at the time of the vaccine rollout

Adding Pembrolizumab to Chemo Ups Survival in Cervical Cancer

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Progression-free and overall survival significantly longer for patients with persistent, recurrent, metastatic cervical cancer

Moderna Vaccine Top for Protection Against COVID-19 Hospitalization

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Vaccine effectiveness higher for Moderna than Pfizer-BioNTech vaccine; both mRNA vaccines have higher VE than Janssen

COVID-19 Has Killed More Americans Than the Spanish Flu Did in 1918

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This happened despite vast gains in scientific knowledge during the past century

Precedent Needed for FDA Approval Decisions When Evidence Lacking

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In seven of 22 cases, approval used new interpretations of original evidence and did not require new evidence

Animal Sedative Driving Rise in Fatal Drug ODs

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In 2019, xylazine contributed to death in 64 percent of cases and almost always also involved fentanyl

Overweight Children With Asthma Less Likely to Respond to Treatment

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Higher body mass index tied to poor response to inhaled corticosteroids

Booster Dose of J&J COVID-19 Vaccine May Increase Immunity

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New research indicates two doses of the vaccine boosts immunity from 74 to 94 percent