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BNT162b2 Still Effective, but Less So, Against Omicron

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Vaccine effectiveness 70 percent compared with 93 percent against hospitalization for COVID-19 during delta predominance

Israel Will Give Fourth COVID-19 Shot to People Older Than 60, Health Workers

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About 60 percent of Israel's 9.4 million people are fully vaccinated with either a recent second dose or booster dose

Negative COVID-19 Test May Be Required After Isolation Among Asymptomatic

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CDC is considering adding extra safeguard after getting some 'pushback' on its Dec. 27 guidance that shortened isolation times

Machine Learning IDs Predictors of Treatment Response in RA

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Machine learning integrating clinical and genomic data can predict methotrexate treatment response in early rheumatoid arthritis

Frail Patients With Nonvalvular A-Fib Less Likely to Receive Anticoagulants

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Frail patients with nonvalvular atrial fibrillation also less likely to receive a direct oral anticoagulant versus warfarin

FDA Approves Pfizer Booster Shots for Children Ages 12 to 15

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Agency also reduced the period people must wait between their second dose and booster shot from six to five months

AAN Updates Guideline for Treatment of Painful Diabetic Neuropathy

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When patients do not experience meaningful improvement with initial therapeutic class, medication from different class should be offered

Most COVID-19-Related EUAs Not Supported by High-Quality Evidence

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Most EUAs were for diagnostic products; most supported by comparisons with previously authorized assays, analytical in vitro studies

Rivaroxaban Improves Clinical Outcomes After COVID-19 Hospitalization

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Risk for thrombotic events reduced after 35 days of rivaroxaban compared with no extended thromboprophylaxis

Dolutegravir-Based ART Superior for Children, Teens With HIV

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Rate of serious adverse events similar for participants receiving dolutegravir, standard care as first-, second-line treatment for HIV-1 infection