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Pfizer Will Ask FDA to Approve Its COVID-19 Vaccine for Children Under 5 Years

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If approved, the two-shot regimen would become the first approved for use in children this young

First Shots Given in Trial of Moderna mRNA-Based HIV Vaccine

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Vaccine uses mRNA technology to deliver HIV-specific antigens that could trigger an immune response against the virus

Aspirin Underutilized for Preeclampsia Prevention

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Findings reported among women at high risk due to prepregnancy diabetes, obesity, and/or chronic hypertension

Lenvatinib + Pembrolizumab Treats Advanced Endometrial Cancer

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Progression-free, overall survival prolonged with lenvatinib plus pembrolizumab versus treating physician's choice of chemotherapy

FDA Gives Moderna COVID-19 Vaccine Full Approval

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Vaccine, which has been available for the age group under emergency use authorization, will be marketed as Spikevax

Long-Acting Cabotegravir Not Necessarily Cost-Effective for PrEP

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Benefits do not necessarily justify large price difference compared with generic F/TDF for men who have sex with men and transgender women

California Universal Health Care System Bill Faces Monday Deadline

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There is also a second bill to fund universal health care, which has a different deadline and does not have to pass on Monday

Three mRNA Vaccine Doses Protective Against Delta, Omicron

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However, odds ratios were higher for omicron suggesting that booster doses are less protective than against delta

CV, Cancer Risk Up With Tofacitinib for Rheumatoid Arthritis

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Incidences of major adverse cardiovascular events, cancers higher with tofacitinib versus TNF inhibitor; criteria for noninferiority not met

Remdesivir May Benefit Adults Early in COVID-19 Course

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Real-world data support the use of remdesivir for hospitalized COVID-19 patients receiving no oxygen or low-flow oxygen