Trials Show Promise for Intravitreal Faricimab in Retinal Disease
Faricimab noninferior to aflibercept for visual acuity gains in neovascular age-related macular degeneration, diabetic macular edema
Risk for Breakthrough SARS-CoV-2 Infection Lower With mRNA-1273
Risk for breakthrough infection and of 60-day hospitalization significantly lower for mRNA-1273 versus BNT162b2 vaccination
Intention to Receive COVID-19 Vaccine Has Grown Faster Among Black Adults
Persistent lower vaccination rate in Black adults might be explained by other factors besides hesitancy
AHA Issues Advisory for Penicillin Reactions in Patients With Severe RHD
Strongly consider oral prophylaxis for patients at elevated risk for cardiovascular compromise following IM injection of benzathine penicillin G
Pfizer Asks FDA to Approve Its Vaccine for the Youngest Children
An FDA advisory panel will weigh the two-dose regimen on Feb. 15
Prevalence of Melatonin Supplement Use Increased Over Time
1999-2000 to 2017-2018 saw increase in reported prevalence of melatonin use across sex and age groups
Racial Disparity Seen in Initiation of Newer Diabetes Meds
Significantly lower rates of initiation seen in Black and American Indian or Alaskan Native individuals
Adding ADT to Radiotherapy Ups Mets-Free Survival in Prostate Cancer
In meta-analysis, adjuvant ADT prolongation also linked to improvement in metastasis-free survival, but not neoadjuvant ADT extension
Remdesivir Offers Some Benefit for Hospitalized COVID-19 Patients
No difference seen for in-hospital mortality, but need for initiation of mechanical ventilation reduced with addition of remdesivir to standard care
Polygenic Score Helps Guide Choice of Chemo for Pediatric AML
Polygenic score based on single nucleotide polymorphisms in the ara-C pathway genes may predict treatment outcomes
