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Intranasal Insulin, Empagliflozin Have Promising Effects on Cognition

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Intranasal insulin increased mPACC-5, modulated fractional anisotropy and cerebral blood flow

Foot/Ankle Injury During Football Career Linked to Foot/Ankle OA

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Cases with foot/ankle OA or forefoot/ankle surgery after retirement had more foot/ankle injury and injections

Pazopanib Well-Tolerated in Young With Primary Multimetastatic Ewing Sarcoma

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No significant toxicities observed in 11 patients included in study; 10 were alive at median follow-up of 2.6 years

New Nonhormonal Drug Approved to Treat Menopause Symptoms

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The once-daily pill elinzanetant is expected to be available within weeks

Hormone Tx Linked to Incidence, Risk for Autoimmune Disease Postmenopause

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Significant increases in risk were observed for all autoimmune diseases except Graves disease and autoimmune hepatitis

Trend Seen for Improved Recurrence-Free Survival With Pembrolizumab in Merkel Cell Carcinoma

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Recurrence-free survival was numerically higher with adjuvant pembrolizumab, but difference was not significant

SGLT-2 Inhibitors Tied to Lower Risk for Autoimmune Rheumatic Diseases in Adults With T2D

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SGLT-2 inhibitors linked lower risk for autoimmune rheumatic diseases compared with sulfonylureas

CHEST: Nerandomilast Slows Decline in FVC in Idiopathic Pulmonary Fibrosis

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No significant difference seen in composite end point of acute exacerbation, hospitalization for respiratory cause, or death

Abemaciclib + Endocrine Therapy Improves Survival in HR-Positive, HER2-Negative Early Breast Cancer

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15.8 percent lower risk for death seen with abemaciclib-ET versus ET in intent-to-treat population

Enzalutamide + Leuprolide Boosts Overall Survival for Prostate Cancer With High Recurrence Risk

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Enzalutamide monotherapy was not superior to leuprolide alone