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The chemotherapy drug Yondelis (trabectedin) has been approved by the U.S. Food and Drug Administration to treat certain advanced or unresectable soft-tissue sarcomas.

FDA Approves Yondelis for Soft-Tissue Sarcoma

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Drug sanctioned for liposarcoma or leiomyosarcoma
Metformin use at high doses seems to be associated with increases in height among children

High-Dose Metformin Linked to Increases in Child Height

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Dose-response relationship between metformin use and increases in height in children, teens
Many physicians are inconsistent or behind schedule in their recommendations for human papillomavirus vaccination

Many Doctors Inconsistent With HPV Vaccine Recommendations

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Sizeable minority does not strongly endorse vaccination nor deliver timely recommendations
Nicotinamide appears to reduce non-melanoma skin cancers by 23 percent when taken twice daily

Nicotinamide Could Protect Against Some Skin Cancers

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High-risk patients who took nicotinamide daily developed fewer non-melanoma lesions
Coagadex (coagulation Factor X) has been approved by the U.S. Food and Drug Administration as the first coagulation factor replacement therapy for people with a rare blood disorder known as hereditary Factor X deficiency.

FDA Approves Coagadex for Rare Clotting Disorder

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First coagulation therapy sanctioned for Factor X deficiency
For patients with inflammatory bowel disease

Low Hep B Vaccine Response Rate Linked to IBD Treatment

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Treatment with infliximab and/or azathioprine associated with weaker response to vaccination
For many Canadian patients with atrial fibrillation

Many Doctors Don’t Explain Stroke, Bleeding Risk in A-Fib

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In substantial proportion of patients, primary care physicians did not provide stroke or bleeding risk
Naproxen alone appears to provide as much relief for low back pain as naproxen plus oxycodone/acetaminophen or cyclobenzaprine

Opioid Added to Rx Naproxen No Help in Low Back Pain

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Adding cyclobenzaprine, oxycodone/acetaminophen to naproxen alone does not improve outcomes
Even if a woman gets a tetanus-containing shot before she conceives

Tdap Appears Safe in Pregnancy Even With Recent Tetanus Shot

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Does not appear to raise risk, even with prior tetanus-containing vaccination
Botulinum toxin injection may help prevent development of atrial fibrillation after coronary artery bypass graft surgery

Botulinum Toxin Might Control A-Fib After CABG Surgery

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Provides substantial atrial tachyarrhythmia suppression without any serious adverse events