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For patients with prediabetes

Sildenafil Improves Insulin Sensitivity in Prediabetes

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Decrease in plasminogen activator inhibitor-1 without affecting tissue-plasminogen activator
Rosuvastatin appears to be more effective than atorvastatin for regression of coronary atherosclerotic plaques

Meta-Analysis: Rosuvastatin May Be Superior for Plaque Regression

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Rosuvastatin more effective than atorvastatin for reversion of coronary atherosclerotic plaques
A new small study is adding evidence to the theory that insulin resistance may play a leading role in some cases of depression. Findings from the study were published online Oct. 12 in Psychiatry Research.

Pioglitazone Found to Help Some With Unremitting Depression

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Insulin resistance may underlie some cases, researchers say
Glucagon-like peptide 1 receptor agonists appear beneficial for postprandial glucose management in type 2 diabetes

GLP-1 Receptor Agonists Can Manage Postprandial Glucose

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Effective for postprandial glucose management in patients with type 2 diabetes on basal insulin
The best approaches to low-dose aspirin prophylaxis for the prevention of preeclampsia seem to be the U.S. Preventive Services Task Force recommendations and universal prophylaxis

Approaches Compared for Aspirin Prophylaxis for Preeclampsia

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Benefits for U.S. Preventive Services Task Force recommendations and for universal prophylaxis
For patients with urinary tract infections

Continuation of Antibiotics for UTI Often Inappropriate

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Antibiotics frequently initiated inappropriately in ER; continuation after admission inappropriate for 68%
Real-world application of pre-exposure prophylaxis medications appears to be effective for the prevention of HIV

Preventive HIV Treatment Shown Effective at Health Clinics

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But uptake of PrEP lower among blacks
For men with type 1 diabetes

Testosterone Levels Not Linked to Autonomic Neuropathy in T1DM

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Lower testosterone concentrations at years 10, 17 not linked to cardiovascular autonomic neuropathy
The risk of anaphylaxis associated with first exposure to intravenous iron is highest for iron dextran and lowest for iron sucrose

Risk of Anaphylaxis Among IV Iron Products Compared

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Risk of anaphylaxis associated with IV iron highest for iron dextran, lowest for iron sucrose
Treatment with ranibizumab is noninferior to panretinal photocoagulation for eyes with proliferative diabetic retinopathy

AAO: Ranibizmab Noninferior to Panretinal Photocoagulation

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Among eyes with proliferative diabetic retinopathy, ranibizumab noninferior at two years