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Breast cancer survivors who take antidepressants while on tamoxifen are not at increased risk for cancer recurrence

Antidepressants Don’t Adversely Affect Tamoxifen Efficacy

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No greater risk of breast cancer recurrence seen
Metformin appears to trigger favorable changes in intestinal bacteria

Metformin Linked to Beneficial Changes in Gut Bacteria

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Drug tied to increased bacteria which produce health-promoting short-chain fatty acids
For patients with Duchenne muscular dystrophy

IV Bisphosphonate Tx Linked to Drop in Bone Turnover in DMD

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Need for therapies with less bone turnover suppression in Duchenne muscular dystrophy
For men with type 2 diabetes and hypogonadotropic hypogonadism

Testosterone Treatment Tied to Improved Insulin Sensitivity

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Increased insulin sensitivity in men with type 2 diabetes and hypogonadotropic hypogonadism
Nearly half of American adults who should be taking cholesterol-lowering drugs don't

CDC: Too Few Taking Needed Cholesterol-Lowering Drugs

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Only half who should are using medications to help prevent cardiovascular disease
Large clinical studies that are sponsored by industry are more likely to report favorable outcomes and less likely to report unfavorable outcomes than those sponsored by the National Institutes of Health

Cardiovascular Trial Sponsorship Significantly Impacts Findings

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Favorable outcomes seven times more likely in industry- versus NIH-sponsored trials
For patients with immunoglobulin A nephropathy

Addition of Immunosuppression No Benefit in IgA Nephropathy

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No improvement in outcomes, more adverse effects for intensive supportive care + immunosuppression
The addition of lixisenatide to usual care does not impact the rate of major cardiovascular events or other serious adverse events among patients with type 2 diabetes and a recent acute coronary syndrome

Lixisenatide Doesn’t Affect Cardiovascular Risk in T2DM

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Findings among patients with type 2 diabetes and recent acute coronary syndrome
For patients with nonspecific chronic low back pain

Vitamin D3, Placebo Both Improve Chronic Low Back Pain

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No significant between-group difference in decrease in mean pain VAS score, mean change in chronic pain
Less frequent laboratory monitoring may be safe for patients receiving isotretinoin for acne as changes in mean values of several laboratory tests do not meet a priori criteria for high-risk

Evidence Doesn’t Support Monthly Labs With Isotretinoin

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Significant changes in values of several laboratory tests, but changes don't meet high-risk criteria