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Cola intake leads to a clinically relevant and statistically significant increase in the bioavailability of erlotinib during esomeprazole treatment

Cola Intake Increases Exposure of Erlotinib

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Findings in patients treated with esomeprazole; likely due to pH-dependent solubility
Statin use is associated with decreased risk of cirrhosis decompensation and death in patients with hepatitis C virus-related compensated cirrhosis

No Need to Avoid Statins in Hep C Compensated Cirrhosis

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Statin use tied to lower risk of decompensation and death in hep C compensated cirrhosis
Use of certain behavioral interventions can reduce the rates of inappropriate antibiotic prescribing during ambulatory visits for acute respiratory tract infections

Behavioral Interventions Can Cut Inappropriate Antibiotic Use

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Significant reductions in rate of inappropriate Rx with accountable justification, peer comparison
Subcutaneous botulinum toxin type A injections appear to safely and effectively reduce chronic neuropathic pain in patients with spinal cord injury

Botox May Reduce Chronic Neuropathic Pain

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Findings in small study of patients with spinal cord injury-associated pain
Exposure to serotonin-norepinephrine reuptake inhibitors in late pregnancy is associated with increased risk of postpartum hemorrhage

Postpartum Hemorrhage Up With Specific Antidepressants

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Risk up with exposure to serotonin-norepinephrine reuptake inhibitors in late pregnancy
For adults with major depressive disorder

CBT May Work As Well As Meds in Major Depressive Disorder

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For adults, similar efficacy for cognitive behavioral therapy and antidepressants
A case of central retinal vein occlusion two days after phendimetrazine use has been documented and published online Feb. 4 in JAMA Ophthalmology.

Central Retinal Vein Occlusion ID’d After Phendimetrazine Use

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Case describes CRVO in patient two days after taking phendimetrazine for weight loss
Influenza infection is associated with increased odds of atrial fibrillation

Influenza Infection Tied to Increased Risk of A-Fib

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Increased risk of atrial fibrillation can be reduced with influenza vaccination
Medical liability reforms are likely to be advanced and challenged in 2016

AMA Highlights Issues Relating to Medical Liability Reform

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New ideas likely to be implemented in 2016 to address existing, developing issues in medical liability
Folic acid consumption in the first trimester is associated with increased risk of gestational diabetes mellitus

Folic Acid Consumption in First Trimester Linked to GDM Risk

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Much higher risk for women with prepregnancy BMI of ≥25 kg/m² taking FA supplements