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March 2016 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for March 2016. This roundup includes the latest...
For patients with Parkinson's disease admitted to the hospital

Under-Dosing Worsens Prognosis for PD Patients With Infection

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Findings among patients with Parkinson's disease admitted to the hospital with pneumonia, UTI
On-demand

Continuous-Flow Production of Pharmaceuticals Feasible

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Continuous-flow synthesis of active drugs demonstrated in compact reconfigurable platform
For children aged 4 to 18 years

Child Mental Health Care Varies Widely in Primary Care Settings

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Prevalence of mental health diagnosis, psychotropic medication prescribing vary across U.S. practices
For statin-treated patients with coronary heart disease

Renal Function Key to Cardiac Outcome in Statin-Treated CHD

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Intrastudy stabilization, increase in eGFR linked to reduced MCVE rate in atorvastatin-treated patients
Omalizumab is effective in patients with moderate-to-severe chronic spontaneous urticaria symptoms and angioedema unresponsive to high doses of antihistamine treatment

Omalizumab Effective for Chronic Spontaneous Urticaria

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Treatment improves quality of life, cuts angioedema recurrence
Oral estradiol therapy is associated with less progression of subclinical atherosclerosis in postmenopausal women when therapy is initiated early in menopause

Early Menopause Estradiol Tx Cuts Atherosclerosis Advance

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Positive effect seen only on carotid-artery intima-media thickness
Baricitinib

Baricitinib Superior to Placebo in Refractory Rheumatoid Arthritis

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Findings based on patients with previous inadequate response to biologics
The American College of Cardiology and the American Heart Association Task Force on Clinical Practice Guidelines has updated the recommendations regarding duration of dual antiplatelet therapy for patients with coronary artery disease. The updated practice guideline was published online March 29 in the Journal of the American College of Cardiology.

Guidelines Updated on Duration of Dual Antiplatelet Tx in CAD

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Longer-duration tx represents trade-off between decreased risk of cardiac events, increased bleeding
For patients with type 2 diabetes newly treated with antidiabetic drugs

Pioglitazone Linked to Increased Risk of Bladder Cancer

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Duration- and dose-response associations for pioglitazone; no correlation for rosiglitazone