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Intraoperative administration of an otic suspension of ciprofloxacin appears to be safe and effective for children requiring tympanostomy tube placement

Intraoperative Administration of OTO-201 Safe in Tube Placement

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Otic suspension of ciprofloxacin safe, effective for children undergoing tympanostomy tube placement
A U.S. Food and Drug Administration safety announcement relating to atrial fibrillation risk associated with bisphosphonates correlated with a reduction in bisphosphonate use

FDA Safety Announcement Affected Bisphosphonate Use

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Four percent decrease in odds of bisphosphonate use each quarter after safety announcement for a-fib risk
Free training is being offered to physicians in medication-assisted treatment

Free Training Being Offered for Substance Use Disorder Tx

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Providers' Clinical Support System offering training comprising online course, live training
Many children who develop urinary tract infections tied to the Escherichia coli bacteria are now failing to respond to antibiotic treatment

Antibiotic Resistance in Pediatric UTIs Up Globally

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Could lead to greater reliance on much more costly intravenous medications
Fewer than half of atrial fibrillation patients at highest risk for stroke are prescribed recommended anticoagulation

Many A-Fib Patients Missing Out on Recommended Anticoagulation

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Less than half at highest risk take recommended anticoagulants
Anti-programmed cell death-1 therapy for metastatic melanoma is associated with the development of immune-related cutaneous events

Melanoma Therapy Tied to Cutaneous Adverse Events

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Anti-programmed cell death-1 therapy tied to lichenoid reactions, eczema, vitiligo
For neonates born before 24 weeks of gestation

Antenatal Corticosteroids Cut Mortality for Early Preemies

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Reduced odds of mortality to discharge with receipt of corticosteroids and active intensive treatment
Early patient-controlled oral analgesia is non-inferior to standard parenteral analgesia for pain management after elective cesarean section

Patient-Controlled Analgesia Non-Inferior After C-Section

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Non-inferior to parenteral analgesia for pain management after elective C-section
For subjects at risk of aspirin-associated upper gastrointestinal events

PA32540 Safe for Patients at Risk of Aspirin-Linked Upper GI Events

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Long-term, once-daily enteric-coated aspirin 325 mg and immediate-release omeprazole 40 mg is safe
In U.S. adolescents

Off-Label Use of Metformin Common in U.S. Adolescents

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Analyses of three databases show use for metabolic syndrome, PCOS, and obesity