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Discontinuation of acetylcholinesterase inhibitors for treatment of Alzheimer's disease is common

Many Patients With Alzheimer’s Disease Discontinue AChEIs

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Adverse effects and cost account for most cases of discontinuation
Lowering of plasma uric acid with febuxostat is associated with a modest reduction in systolic blood pressure in patients with type 1 diabetes mellitus

Plasma Uric Acid Lowering Tied to Drop in Systolic BP in T1DM

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Febuxostat has modest BP-lowering effect, with no impact on arterial stiffness, urinary nitric oxide
The bacterial cell wall-derived muramyl dipeptide postbiotic lowers adipose inflammation and reduces glucose intolerance in obese mice

Postbiotic Could Lower Glucose, Inflammation in Obesity

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MDP postbiotic linked to reduction in hepatic insulin resistance during obesity, low-level endotoxemia
A fatal case of propofol-induced acute necrotizing pancreatitis has been described in a case report published online April 10 in the Journal of Clinical Pharmacy and Therapeutics.

Fatal Case of Suspected Propofol-Induced Pancreatitis Described

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57-year-old woman developed severe abdominal pain with nausea, vomiting after thyroidectomy
The U.S. Food and Drug Administration on Tuesday posted warning letters to 14 companies that are illegally selling more than 65 unproven cancer treatments.

FDA Warns Companies Selling Fraudulent Cancer Treatments

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The unapproved products are often advertised as 'natural' and labeled as supplements
The prescription drug abuse epidemic in the United States might be associated with a higher mortality rate than has been reported previously

CDC: Opioid-Related Mortality Rate Might Be Underestimated

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Death certificates from drug-linked infections may not label opioids as possible cause
Illicit cannabis use increased significantly more in states that passed medical marijuana laws than in other states

Illicit Marijuana Use Up in States With Legal Medical Use

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Cannabis use disorder is also rising faster in states with legalization laws

T2DM Risk Cut by Variant in Sulfonylurea Receptor Encoder

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Missense variant in ABCC8 gene also linked to reduced risk of coronary heart disease
Hepatitis B virus reactivation is a safety concern for patients with HBV and hepatitis C virus coinfection receiving direct-acting antiviral agents

HBV Reactivation Is Concern With DAA Tx in HBV-HCV Coinfection

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29 cases of HBV reactivation reported in patients with coinfection receiving direct-acting antivirals
New research offers a checklist that helps determine whether it is safe for patients with type 1 diabetes to drive. The findings were published online April 12 in Diabetes Care.

Doctors Encouraged to Assess Driving Risks for T1DM Patients

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Researchers say new checklist can help determine when hypoglycemia should keep patients off the road