Early Intensive Treatment May Improve Long-Term MS Outcomes
Mean five-year change lower in Expanded Disability Status Scale score with early intensive treatment
Combo Regimens Effective for Tx of Metastatic Renal Cell Cancer
Two large trials show benefits for pembrolizumab-axitinib and avelumab-axitinib versus sunitinib
Plazomicin Noninferior to Meropenem for Complicated UTI
In second study, plazomicin may be beneficial for carbapenem-resistant Enterobacteriaceae infections
Experimental Test May Quickly Diagnose Sepsis
Microelectrode device analyzes a patient's blood, provides results in as quickly as 2.5 minutes
FDA Head Says Feds May Intervene to Cut Vaccine Exemptions
If states do not change lax vaccine laws, federal authorities may be forced to take action
Prenatal Fluconazole Exposure Increases Neonatal Risks
Any exposure increases spontaneous abortion risk; cardiac septal defects up for use in early pregnancy
Darolutamide Slows Spread of Castration-Resistant Prostate Cancer
Significant survival benefit seen, adverse events similar between darolutamide and placebo
Inappropriate Use of Fentanyl Preps Seen Despite Awareness
Claims data show many prescribed transmucosal immediate-release fentanyl were opioid-nontolerant
Discharge Opioid Rx for Heart Dz Patients May Impact Follow-Up
Findings seen in patients with admitting diagnosis of acute coronary syndrome, decompensated heart failure
Risk Factors ID’d for Diffuse Large B-Cell Lymphoma Mortality
In older patients, risk factors include advanced age, DLBCL stage, Charlson Comorbidity Index