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Men should be included in clinical trials of new breast cancer treatments

FDA: Men Should Be Included in Breast Cancer Clinical Trials

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Draft guidance that men be included in breast cancer trials issued by the FDA on Aug. 26
The combination of selinexor and dexamethasone seems effective in treating patients with multiple myeloma that has not responded to standard therapies

Novel Therapy Treats Triple-Class Refractory Multiple Myeloma

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Partial response or better observed in 26 percent of patients receiving oral selinexor-dexamethasone
Antibiotic prescriptions are associated with a higher risk for rheumatoid arthritis

Antibiotic Use Tied to Higher Risk for Rheumatoid Arthritis

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Findings show a dose- or frequency-dependent association; all antibiotic classes linked to higher odds for RA
Children with mild asthma can use inhalers as needed

As-Needed Inhaler Use an Option for Children With Mild Asthma

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Study in African-American children shows symptom-based adjustment of inhaled corticosteroids is feasible
Use of a four-component polypill can effectively reduce the risk for major cardiovascular events

Low-Cost, Fixed-Dose Polypill Reduces Risk for Major CV Events

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Drop in risk for major cardiovascular events even greater for those with high adherence to polypill
Participants in a weight loss intervention can lose weight regardless of psychiatric medication use

Weight Loss Feasible Regardless of Psychiatric Meds Use

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Weight loss amount similar for women taking and not taking psychiatric medications
Ninety-two percent of human papillomavirus (HPV)-related cancers are attributable to HPV types targeted by the 9-valent HPV vaccine

Most HPV-Linked Cancers Due to Types Targeted by 9vHPV Vaccine

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In 2012 to 2016, 92 percent of cancers attributable to HPV due to HPV types targeted by 9vHPV vaccine
Patient confidentiality rule changes meant to help fight the opioid crisis in the United States have been proposed by the federal government.

Patient Confidentiality Rule Changes Aim to Fight U.S. Opioid Crisis

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A patient's consent to share their information would still be required
Increasing blood pressure medications at hospital discharge for elderly patients hospitalized with noncardiac conditions does not improve long-term outcomes and is tied to short-term harms

Intensifying BP Meds at Hospital Discharge May Harm Elderly

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Risk for readmissions and adverse effects higher, no long-term benefit for BP control or cardiac risk
Some cities in Texas are susceptible to measles outbreaks

Some Cities in Texas Susceptible to Measles Outbreaks

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If vaccination rates continue to drop, considerable increase in potential outbreak predicted