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November 2019 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for November 2019. This roundup includes the latest...
Obesity may cause a differential response to antiarrhythmic drugs used to suppress atrial fibrillation

Obesity Mediates Response to Antiarrhythmic Drugs in A-Fib

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Reduced response to sodium versus potassium channel blocker AADs seen in obese patients, mice
Continuous use of proton pump inhibitor therapy is associated with an increased risk for acute gastroenteritis during winter epidemic periods with peak circulation of enteric viruses

Continuous PPI Use May Increase Risk for Acute Gastroenteritis

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Risk for acute gastroenteritis icreased for all ages combined and for those aged 45 to 64, 65 to 74, ≥75
Diet pill and laxative use for weight control are associated with increased odds of subsequent first eating disorder diagnosis

Diet Pill, Laxative Use in Women Tied to Later Eating Disorder Dx

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Odds of incident eating disorder diagnosis up with use of diet pill, laxative for weight control
More than 12 percent of patients with atherosclerotic cardiovascular disease report nonadherence to medications due to costs

U.S. Adults With ASCVD Report Skipping Meds Due to Costs

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Age <65 years, female sex, high comorbidity burden independently linked to cost-related nonadherence
From 2000 to 2017

Exposure to Psychoactive Substances Up From 2000 to 2017

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Exposure to most substances decreased, but significant increases seen in marijuana, nutmeg, and kratom
Levetiracetam

Three Meds Equal as Second-Line Therapy for Status Epilepticus

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Levetiracetam, fosphenytoin, valproate treat seizures unresponsive to benzodiazepine in children, adults
The addition of a second and third fracture-associated drug is associated with an increase in hip fracture risk

Taking Multiple Fracture-Linked Meds Ups Risk for Hip Fracture

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Addition of second and third fracture-associated drugs linked to increased risk for women and men
Adjusting glucose thresholds for hypoglycemia and hyperglycemia alarms in continuous glucose monitoring can help achieve better glucose control in patients with type 1 diabetes mellitus

Alarm Settings of CGM Systems Impact Glucose Control in T1DM

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Adjusting glucose thresholds for alarms linked to less time spent in hypoglycemia, hyperglycemia
In an expert panel consensus

Dermatologists Issue Consensus Guideline for Opioid Prescribing

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For most uncomplicated procedures, postop pain can be managed with acetaminophen and/or ibuprofen