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For pediatric patients with acute myeloid leukemia

Dexrazoxane Preserves Cardiac Function in Pediatric Leukemia

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Beneficial for patients with AML receiving anthracyclines, with no impact on event-free, overall survival
Among patients with heart failure

For Those With Heart Failure, ACE2 Concentrations Up in Men

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Use of ACE inhibitors, ARBs not tied to higher plasma ACE2 concentrations in those with heart failure
After the COVID-19 emergency declarations

Pediatric Vaccine Ordering Has Decreased During COVID-19

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Decrease seen in VFC-funded APIC-recommended childhood vaccines after national emergency declaration
There is a crude correlation between vitamin D levels and the number of COVID-19 cases and COVID-19 mortality

Crude Link ID’d for Vitamin D Levels, COVID-19 Cases, Death

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Vitamin D levels severely low in aging population, the most vulnerable population to COVID-19
High-dose anakinra

Anakinra May Reduce Systemic Inflammation in COVID-19

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At 21 days, survival was 90 percent in anakinra group versus 56 percent in standard treatment group
For patients with COVID-19

Triple Antiviral Therapy Promising for Mild-to-Moderate COVID-19

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Duration of viral shedding shorter with combination of lopinavir-ritonavir, ribavarin, interferon beta-1b
The presence of a residual shunt after patent foramen ovale closure is associated with an increased risk for recurrent stroke or transient ischemic attack

Residual Shunt After PFO Closure Linked to Higher Risk for Stroke

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Risk for recurrent stroke, transient ischemic attack increased with presence of residual shunt
Hydroxychloroquine is not associated with an increased or decreased risk for intubation or death among patients with COVID-19 admitted to the hospital

Hydroxychloroquine Has No Impact on Outcomes in COVID-19

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No link seen between use of the drug and risk for composite end point of intubation or death
Angiotensin-converting enzyme inhibitor and/or angiotensin receptor blocker use is not associated with COVID-19 test positivity

ACE Inhibitor/ARB Use Not Tied to COVID-19 Test Positivity

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No significant association identified in overlap propensity score weighting analysis
Among prostate cancer patients

Risk for SARS-CoV-2 Lower for Prostate Cancer Patients on ADT

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Risk reduced fourfold with androgen-deprivation therapy versus other treatment for prostate cancer