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In a Notes from the Field report

Case Study: Methylmercury Toxicity Found From Skin-Lightening Cream

Patient admitted to hospital with symptoms that included blurry vision, unsteady gait, difficulty speaking
Buprenorphine treatment may be needed for several years after an opioid overdose to reduce the risk of overdose and other adverse events

Overdose, Relapse After Buprenorphine Discontinuation High

The longer patients continue with buprenorphine treatment, the lower their risk of adverse outcomes
Use of antioxidants and other dietary supplements before and during chemotherapy is associated with worse survival outcomes for patients with breast cancer

Antioxidant, Supplement Use May Worsen Breast Cancer Outcomes

Disease-free, overall survival poorer with vitamin B12 use before and during chemotherapy
Most children with non-β-lactam antibiotic allergy can be delabeled

Most Children Do Not Have Positive Results to Antibiotic Challenge

Positive results for only 18 percent of challenge tests to non-β-lactam antibiotics
Regular recreational cannabis use is associated with alterations in cardiac structure and function

Regular Cannabis Use May Cause Adverse Cardiac Changes

Changes in left ventricular size, subclinical dysfunction reported for regular cannabis use versus rare/no use
Obesity is associated with an increased risk for cardiotoxicity among patients receiving treatment for breast cancer

Obesity May Up Cardiotoxicity Risk From Breast Cancer Therapy

Obesity independently associated with treatment-related cardiotoxicity in breast cancer patients
In 2018

12 Million U.S. Residents Drove Under Influence of Marijuana in 2018

Prevalence of driving under the influence increased among men, those aged 16 to 34 years
The out-of-pocket costs for out-of-network care grew rapidly for privately insured Americans from 2012 to 2017

Patient Share of Out-of-Network Costs Rising

From 2012 to 2017, out-of-pocket costs nearly doubled for out-of-network hospital care
Gastroesophageal reflux disorder symptoms are common

Half of Patients on PPIs for GERD Still Have Persistent Symptoms

Heartburn, regurgitation reported by 54.1 percent of participants taking proton pump inhibitor daily
Among patients with metastatic renal cell carcinoma

Tivozanib Bests Sorafenib in Metastatic Renal Cell Carcinoma

Progression-free survival longer in those receiving tivozanib as third- or fourth-line therapy