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Two Experimental Drugs for Rare, Inherited Alzheimer Disease Disappoint
Both drugs designed to target and neutralize amyloid beta in the brain
Resting-State EEG Can Predict Sertraline Treatment Outcomes
Sertraline-predictive EEG signature examined in four independent depression treatment sets
Hexavalent Vaccine Included in Vaccines for Children Program
DTaP-IPV-Hib-HepB vaccine has safety profile consistent with licensed comparator vaccines
GI Bleeding in OAC-Treated A-Fib Patients Indicates CRC Risk
Lower-GI bleeding tied to high absolute risks for CRC in patients receiving oral anticoagulants for a-fib
Speaker Conflicts of Interest May Bias Testimony About Drugs
Public speakers with conflict of interest more likely to provide positive testimony of psychiatric drug
Recommendations Developed for Management of Complex ADHD
Treatment should include evidence-based approaches and account for coexisting conditions
Reference Pricing Linked to Lower Prices Paid by Employers
Cost sharing by employees lower, but time lag seen in physicians' prescribing habits
Visit Adherence, Visual Acuity Linked in Macular Degeneration
Late, very late groups saw fewer letters than patients in on-time group for two measures of visit adherence
Kratom Seems Safe for Pain, Anxiety, Opioid Withdrawal
Kratom most commonly used daily; few serious adverse events self-reported among users
Meta-Analyses Link Rosiglitazone to Increased Cardiovascular Risk
Authors call for sharing of individual patient data to strengthen meta-analyses focused on safety
