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Potentially Inappropriate Medications Linked to Frailty at Cancer Diagnosis

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Each additional Geriatric Oncology-PIM linked to 66 percent increase in odds of being mildly, moderate-to-severely frail at diagnosis

β-Blockers Not Beneficial After MI Without Reduced Left Ventricular Ejection Fraction

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Second study shows beneficial effects for patients with myocardial infarction and mildly reduced LVEF

Women Have Worse Outcomes Than Men With Beta-Blockers After Acute MI

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Incidence of primary end point of death, MI, heart failure hospitalization up with beta-blockers in women, but not in men

FDA Now Providing Daily Updates on Adverse Events

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To increase transparency, the agency is publishing data from the FDA Adverse Event Reporting System daily rather than quarterly

Semaglutide Not Linked to Increased Risk of Eye Disorders, Diabetic Retinopathy

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Semaglutide linked to increased risk of nonarteritic anterior ischemic optic neuropathy, but evidence remains insufficient to establish definitive conclusion

COVID-19 mRNA Vaccine Targeting Omicron JN.1 Lineage Safe

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No significant increases seen in rate of hospital contacts for any of 29 adverse events in 28-day risk period after vaccination

GLP-1 Receptor Agonist Use Linked to Nonarteritic Anterior Ischemic Optic Neuropathy

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Association seen in seniors with type 2 diabetes; greater associations seen for semaglutide and liraglutide

Glipizide Linked to Highest MACE-4 Risk in Individuals With Type 2 Diabetes

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Highest risk seen with glipizide versus other sulfonylureas and DPP4 inhibitors as second-line therapy

Standardization Needed for Dialysis Initiation in Pregnancy

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Women who started dialysis during pregnancy more often had adverse maternal and fetal outcomes

GLP-1 Receptor Agonist Use in T2D Tied to Increased Risk for GERD, GERD Complications

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Risk ratios were 1.27 and 1.55 for GERD and its complications during a median follow-up of three years for GLP-1 RA versus SGLT-2 inhibitor users