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Tag: Ulcerative Colitis

New warnings about an increased risk of thrombosis and of death among ulcerative colitis patients taking the 10 mg twice daily dose of the drug tofacitinib (Xeljanz

FDA: Blood Clot, Death Risk Up With Higher Dose of Tofacitinib

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Increased risk seen with 10 mg dose of tofacitinib used for treating ulcerative colitis
Marketplace introduction of infliximab has not resulted in reductions in the population rates of inflammatory bowel disease-related hospitalizations or intestinal resections or colectomies

Infliximab Introduction Has Not Cut IBD-Related Hospitalizations

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Introduction of infliximab did not lead to drop in hospitalization, intestinal resection, colectomy
A new test can predict the course of inflammatory bowel disease in patients

Biomarker Test Predicts Mild, Serious IBD in Newly Diagnosed

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Test based on genetic signature of CD8 T cells during active disease
Low body mass index among men entering adult life is associated with an increased incidence of Crohn disease and ulcerative colitis up to 40 years later

In Men, Low BMI Tied to Later Inflammatory Bowel Disease

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Risk lasts through 40 years of adulthood for underweight adolescent men
Recommendations have been developed for management of adults with ulcerative colitis; the American College of Gastroenterology clinical guideline was published online Feb. 21 in the American Journal of Gastroenterology.

Recommendations Developed for Ulcerative Colitis Management

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Guidelines address diagnosis, treatment, and overall clinical management of adult patients
There is discordance in communication priorities for patients with ulcerative colitis and their gastroenterology physicians

Patient, Doctor Communication Priorities Differ in Ulcerative Colitis

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Second study highlights importance of recognizing the emotional impact of ulcerative colitis
A new clinical guideline from the American Gastroenterological Association published Dec. 18 in Gastroenterology focuses on the medical management of patients with mild-to-moderate ulcerative colitis.

Guideline Issued for Treatment of Mild/Moderate Ulcerative Colitis

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Standard-dose mesalamine or diazo-bonded 5-ASA recommended versus low-dose mesalamine
Psoriasis appears to be significantly associated with inflammatory bowel disease

Psoriasis Linked to Increased Risk for Inflammatory Bowel Disease

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Significant associations observed between psoriasis and risk for Crohn's disease, ulcerative colitis
Loss to follow-up is common with inflammatory bowel disease

Loss to Follow-Up Common With IBD, But Many Have Flare-Ups

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Predictors of follow-up loss are long travel time and low C-reactive protein levels at diagnosis
U.S. Food and Drug Administration approval of Xeljanz (tofacitinib) has been expanded to include adults with active moderate-to-severe ulcerative colitis

FDA Approves New Treatment for Ulcerative Colitis

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First oral medication approved for chronic use in moderate-to-severe active ulcerative colitis